Assunta
Cirella
Researcher to 2024
Claudia Augusta
Di Trani
Researcher to 2023
Publications by the researcher in collaboration with Claudia Augusta Di Trani (11)
2023
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Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models
Oncoimmunology, Vol. 12, Núm. 1, pp. 2147317
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Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis
Journal for immunotherapy of cancer, Vol. 11, Núm. 11
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Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity
Cancer immunology research, Vol. 11, Núm. 2, pp. 184-198
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Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists
Molecular Therapy - Nucleic Acids, Vol. 33, pp. 668-682
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Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure
Molecular Therapy - Nucleic Acids, Vol. 33, pp. 599-616
2022
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Advances in mRNA-based drug discovery in cancer immunotherapy
Expert Opinion on Drug Discovery, Vol. 17, Núm. 1, pp. 41-53
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Novel strategies exploiting interleukin-12 in cancer immunotherapy
Pharmacology and Therapeutics, Vol. 239
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Overcoming the limitations of cytokines to improve cancer therapy
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 107-141
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Synergistic antitumor response with recombinant modified virus Ankara armed with CD40L and CD137L against peritoneal carcinomatosis
OncoImmunology, Vol. 11, Núm. 1
2021
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Mouse models of peritoneal carcinomatosis to develop clinical applications
Cancers, Vol. 13, Núm. 5, pp. 1-11
2020
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Interleukin-12 message in a bottle
Clinical Cancer Research, Vol. 26, Núm. 23, pp. 6080-6082