Publications (129) José Ángel Martínez Climent publications

filter_list

2025

  1. Co-targeting of epigenetic regulators and BCL-XL improves efficacy of immune checkpoint blockade therapy in multiple solid tumors

    Molecular Cancer, Vol. 24, Núm. 1

  2. Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

    Biomedicines, Vol. 13, Núm. 3

  3. IL-10 from tumoral B cells modulates the diffuse large B-cell lymphoma microenvironment and response to immunotherapy

    Blood, Vol. 145, Núm. 23, pp. 2746-2761

  4. Loss of CYLD promotes splenic marginal zone lymphoma

    HemaSphere, Vol. 9, Núm. 3

  5. Metabolic Heterogeneity in Diffuse Large B-Cell Lymphoma Cells Reveals an Innovative Antimetabolic Combination Strategy

    Cancers, Vol. 17, Núm. 3

2024

  1. Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling

    BIORXIV

  2. Not so natural, not so killers

    Blood

  3. Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma

    Blood cancer discovery, Vol. 5, Núm. 3, pp. 146-152

2023

  1. Activation of the PP2A-B56α heterocomplex synergizes with venetoclax therapies in AML through BCL2 and MCL1 modulation

    Blood, Vol. 141, Núm. 9, pp. 1047-1059

  2. Chronic docosahexaenoic acid supplementation improves metabolic plasticity in subcutaneous adipose tissue of aged obese female mice

    Journal of Nutritional Biochemistry, Vol. 111

  3. Differential remodeling of subcutaneous white and interscapular brown adipose tissue by long-term exercise training in aged obese female mice

    Journal of Physiology and Biochemistry, Vol. 79, Núm. 2, pp. 451-465

  4. Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance

    Nature Communications, Vol. 14, Núm. 1

  5. Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma

    Nature Medicine, Vol. 29, Núm. 3, pp. 632-645

  6. Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis

    Blood, Vol. 141, Núm. 21, pp. 2615-2628

  7. Venetoclax improves CD20 immunotherapy in a mouse model of MYC/BCL2 double-expressor diffuse large B-cell lymphoma

    Journal for immunotherapy of cancer, Vol. 11, Núm. 2

2022

  1. Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma

    Science Advances, Vol. 8, Núm. 3

  2. The alternative RelB NF-κB subunit is a novel critical player in diffuse large B-cell lymphoma

    Blood, Vol. 139, Núm. 3, pp. 384-398

2021

  1. Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- And high-risk myeloma

    Blood, Vol. 137, Núm. 1, pp. 49-60

  2. Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death

    Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285

2020

  1. B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

    Leukemia, Vol. 34, Núm. 4, pp. 1158-1162