Juan
Dubrot Armendáriz
Profesional Investigador
Centro de Investigación Médica Aplicada
Pamplona, España
2026
2025
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In vivo CRISPR screening in head and neck cancer reveals Uchl5 as an immunotherapy target
Nature Communications , Vol. 16, Núm. 1
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Leveraging epigenetic alterations in pancreatic ductal adenocarcinoma for clinical applications
Seminars in Cancer Biology, Vol. 109, pp. 101-124
2023
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Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening
Nature Communications, Vol. 14, Núm. 1
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Protocol for in vivo CRISPR screening using selective CRISPR antigen removal lentiviral vectors
STAR Protocols, Vol. 4, Núm. 1
2022
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In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
Nature Immunology, Vol. 23, Núm. 10, pp. 1495-1506
2015
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Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12
Cancer Research, Vol. 75, Núm. 3, pp. 497-507
2014
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Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus
PLoS ONE, Vol. 9, Núm. 1
2012
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Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanism
OncoImmunology, Vol. 1, Núm. 9, pp. 1527-1536
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Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic semliki forest virus encoding IL-12
Molecular Therapy, Vol. 20, Núm. 9, pp. 1664-1675
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Liver Gene Transfer of Interkeukin-15 Constructs That Become Part of Circulating High Density Lipoproteins for Immunotherapy
PLoS ONE, Vol. 7, Núm. 12
2011
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Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes
Cancer Research, Vol. 71, Núm. 3, pp. 801-811
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 11, pp. 1621-1631
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Dendritic cells adhere to and transmigrate across lymphatic endothelium in response to IFN-α
European Journal of Immunology, Vol. 40, Núm. 11, pp. 3054-3063
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Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells
European Journal of Immunology, Vol. 40, Núm. 12, pp. 3389-3402
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
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Interferon producing killer dendritic cells (IKDC): A matter of controversy
Inmunologia, Vol. 29, Núm. 1, pp. 50-55
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Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria
Journal of Hepatology, Vol. 52, Núm. 3, pp. 417-424