
Cristian
Smerdou Picazo
Profesional Investigador
Argitalpenak (93) Cristian Smerdou Picazo argitalpenak
2025
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COVID-19 mRNA vaccines are effective at stopping a nosy virus
Molecular Therapy Nucleic Acids
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Immunocytokines based on IL-12 for cancer therapy: Enhancing efficacy and reducing toxicity
International Review of Cell and Molecular Biology (Elsevier Inc.)
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Targeting PD-1+ T cells with small-format immunocytokines enhances IL-12 antitumor activity
Molecular Therapy, Vol. 33, Núm. 1, pp. 297-316
2024
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A Dual-Armed Oncolytic Virus Shows Clinical Efficacy in Advanced Solid Cancers
Clinical Cancer Research, Vol. 30, Núm. 17, pp. 3649-3651
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Cell-specific delivery of CRISPR-Cas9 with pseudotyped lentiviral particles: Just change the envelope
Molecular Therapy Nucleic Acids
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Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity
ANTIBODIES, Vol. 13, Núm. 2
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DNA electroporation in a vacuum: A “shocking” innovation for vaccines
Molecular Therapy Nucleic Acids
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Effective cancer immunotherapy combining mRNA-encoded bispecific antibodies that induce polyclonal T cell engagement and PD-L1-dependent 4-1BB costimulation
Frontiers in Immunology, Vol. 15
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Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies
British Journal of Cancer, Vol. 130, Núm. 5, pp. 869-879
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Self-Amplifying RNA: A Second Revolution of mRNA Vaccines against COVID-19
Vaccines, Vol. 12, Núm. 3
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Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy
eBioMedicine, Vol. 103
2023
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AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity
Biomedicine and Pharmacotherapy, Vol. 169
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Checkpoint blockade meets gene therapy: Opportunities to improve response and reduce toxicity
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 43-86
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JNK Activation in Alzheimer’s Disease Is Driven by Amyloid β and Is Associated with Tau Pathology
ACS Chemical Neuroscience
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JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding
ACS Chemical Neuroscience, Vol. 14, Núm. 11, pp. 2074-2088
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Local Delivery of Immunomodulatory Antibodies for Gastrointestinal Tumors
Cancers, Vol. 15, Núm. 8
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Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses
Cancer Letters, Vol. 561
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Photodynamic nasal SARS-CoV-2 decolonization shortens infectivity and influences specific T-Cell responses
Frontiers in Cellular and Infection Microbiology, Vol. 13
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Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice
Aging Cell, Vol. 22, Núm. 3
2022
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A minimal bile salt excretory pump promoter allows bile acid-driven physiological regulation of transgene expression from a gene therapy vector
Cell and Bioscience, Vol. 12, Núm. 1