A Domino Michael/Dieckmann Process as an Entry to alpha-(Hydroxymethyl)glutamic Acid
- Aydillo, C. 1
- Jiménez-Osés, G. 2
- Avenoza, A. 1
- Busto, J.H. 1
- Peregrina, J.M. 1
- Zurbano, M.M. 1
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1
Universidad de La Rioja
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2
University of California Los Angeles
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ISSN: 0022-3263
Year of publication: 2011
Volume: 76
Issue: 17
Pages: 6990-6996
Type: Article
More publications in: Journal of Organic Chemistry
Abstract
A domino process that involves a Michael-type addition followed by a Dieckmann reaction mediated by the participation of the cyclic carbamate group is the key step in the synthesis of both enantiomers of α-(hydroxymethyl) glutamic acid (HMG). © 2011 American C emical Society.