Hiperparatiroidismo primario e hipoparatiroidismos

Abstract

The most common clinical presentation of primary hyperparathyroidism (HPP) is asymptomatic hypercalcemia. Measurement of serum intact paratohormone (iPTH) is necessary to diagnose primary hyperparathyroidism (HPP). in patients with vitamin O in the normal range. HPP Surgery criteria includes serum calcium concentration > 1.0 mg/dL above the upper limit of normal, creatinine clearance < 60 mL/min, T score < -2.5 at any level and age less than 50 years. Normocalcemic hyperparathyroidism is a new variant of hyperparathyroidism, which must be confirmed at least two times. It must be diagnosed by exclusion of other causes of secondary hyperparathyroidism. Natural history of asymptomatic and normocalcemic HPP notes that it usually does not evolve to hypercalcemia. Hypoparathyroidism presents hypocalcemia and low level of PTH. The condition can be inherited, but it is usually encountered after thyroid or parathyroid gland surgery, and it can be caused by immune system-related damage as well as a number of rarer causes. The diagnosis is made with blood tests, and other investigations such as genetic testing depending on the results. The treatment of hypoparathyroidism consists ofcalcium replacement and vitamin D.