Tratamiento de la osteoporosisosteoporosis en la mujer premenopáusica y posmenopáusica. Osteoporosis en el varón
- Díaz-Guerra, G. Martínez
- Iglesias, S. Guadalix
- Miguel, G. Allo
ISSN: 0304-5412
Año de publicación: 2018
Título del ejemplar: Enfermedades óseas Osteoporosis. Paget óseo. Síndrome de dolor regional complejo
Serie: 12
Número: 60
Páginas: 3506-3514
Tipo: Artículo
Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado
Resumen
The treatment of osteoporosis should be comprehensive and include lifestyle measures, physical exercise, appropriate calcium and vitamin D intake and, if indicated, drug treatment. At present, there are various therapeutic options whose efficacy and safety have been well contrasted, especially for osteoporosis in postmenopausal women. Oral bisphosphonates (alendronate, risedronate) are the treatment of choice in most cases, but there are other options (teriparatide, denosumab, intravenous zoledronate) which should be used on a very individual basis, depending on factors such as age, the presence or otherwise of frailty fractures, comorbidities, etc. Osteoporosis is a chronic disease that requires long-term treatment and follow-up. However, the duration of drug treatment and the possibility of discontinuing and/or replacing a drug for another are decisions that require in-depth knowledge of the patient's clinical circumstances, which can change throughout the course of the disease, and of the benefit-risk profile of the different drugs. Osteoporosis in premenopausal women and men is usually secondary to underlying disease. The baseline disease should always be treated, although the same recommendations for calcium and vitamin D intake and physical exercise still apply. The current drugs for women of reproductive age have major limitations, and are reserved for particularly severe cases (frailty fractures, for example).
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