Termoterapia transpupilar en neovascularización subretiniana oculta secundaria a degeneración macular asociada a la edadPrimeros resultados

  1. A Salinas Alamán
  2. A García Layana
  3. JR Juberías Sánchez
  4. H Sánchez Tocino
  5. LM Sádaba Echarri
  6. J Moreno Montañés
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2002

Volume: 77

Issue: 11

Pages: 617-621

Type: Article

DOI: 10.4321/S0365-66912002001100006 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Purpose: To determine the efficacy of transpupillary thermotherapy (TTT) to treat choroidal neovascularization (CNV) in patients with age-related macular degeneration (ARMD). Patients and Methods: Eight patients (ten eyes) with occult CNV were treated by TTT. A 810 nm diode laser was used to perform TTT. The diode laser was delivered through a panfunduscopic contact lens. Results: Three eyes showed a visual acuity improvement and a decrease in exudation on fluorescein angiography. Four eyes remained stable. Nevertheless, lesions worsened after treatment in three cases. One of these cases suffered an overtreatment. Conclusions: TTT may be a useful therapy in some cases of CNV in patients with age-related macular degeneration. Randomized and multicentric studies are necessary to stablish precise indications of this therapy.

Bibliographic References

  • Oosterhuis, JA, Journee-de Korver, HG, Kakebeeke-Kemme, HM, Bleeker, JC. (1995). Transpupillary thermotherapy in choroidal melanomas. Arch Ophthalmol. 113. 315-321
  • Reichel, E, Berrocal, AM, Ip, M, Kroll, AJ, Desai, V, Duker, JS. (1999). Transpupillary thermotherapy of occult subfoveal choroidal neovascularization in patients with age-related macular degeneration. Ophthalmology. 106. 1908-1914
  • Newsom, RS, McAlister, JC, Saeed, M, McHugh, JD. (2001). Transpupillary thermotherapy (TTT) for the treatment of choroidal neovascularization. Br J Ophthalmol. 85. 173-178
  • Mainster, MA, Reichel, E. (2000). Transpupillary thermotherapy for age-related macular degeneration: long-pulse photocoagulation, apoptosis, and heat shock proteins. Ophthalmic Surg Lasers. 31. 359-373
  • Desmettre, T, Maurage, CA, Mordon, S. (2001). Heat shock protein hyperexpression on chorioretinal layers after transpupillary thermotherapy. Invest Ophthalmol Vis Sci. 42. 2976-2980
  • Flower, RW, von Kerczek, C, Zhu, L, Ernest, A, Eggleton, C, Topoleski, LD. (2001). Theoretical investigation of the role of choriocapillaris blood flow in treatment of subfoveal choroidal neovascularization associated with age-related macular degeneration. Am J Ophthalmol. 132. 85-93
  • (2001). Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization: Verteporfin in photodynamic therapy report 2. Am J Ophthalmol. 131. 541-560