La piel como signo de alarma de neoplasias
- Ivars Lleó, M.
- Giménez de Azcárate, A.
- España Alonso, Agustín
ISSN: 0304-5412
Year of publication: 2014
Issue Title: Actualidad clínico-terapéutica (III)
Series: 11
Issue: 69
Pages: 4132-4136
Type: Article
More publications in: Medicine: Programa de Formación Médica Continuada Acreditado
Abstract
The skin is is one of the most accesible organs, so it should never be overlooked in systemic disease. Skin often reflects internal processes, and the awareness of this leads us to consider malignancy as a potencial cause for many cutaneous abnormalities. It's important for clinicians in general to be familiar with cutaneous signs which can lead to an early diagnosis of neoplasia. Examination of the skin has the advantage of revealing important information about the patient's condition without requiring the use of invasive techniques.
Bibliographic References
- Ahronowitz I, Harp J, Shinkai K. Etiology and management of pyoderma gangrenosum: a comprehensive review. Am J Clin Dermatol. 2012;13:191-211.
- Balagula Y, Staus DJ, Pulitzer MP, Lacouture ME. Necrobiotic xanthogranuloma associated wirh immunoglobulin M Paraproteinemia in a patient with Waldestrom macroglobulinemia. J Clin Oncol. 2011;29:e305-7.
- Bell HK, Poston GJ, Vora J, Wilson NJE. Cutaneous manifestations of the malignant carcinoid syndrome. Br J Dermatol. 2005;152:71-5.
- Busam KJ, Sachs DL, Coit DG, Halpern A, Hwu WJ. Eruptive melanotic macules and papules associated with adenocarcinoma. J Cutan Pathol. 2003;30:463-9.
- Chiu ML, Tang MB. Generalized granuloma annulare associated with gastrointestinal stromal tumour: case report and review of clinical features and management. Clin Exp Dermatol. 2008;33:469-71.
- Chodkiewicz HM, Cohen PR. Paraaneoplastic erythema annuare centrifugum eruption: PEACE. Am J Clin Dermatol. 2012;13:239-46.
- Chung VQ, Sci M, Moschella SL, Zembowicz A, Liu V. Clinical and pathologic findings of paraneoplastic dermatoses. J Am Acad Dermatol. 2006;54:745-62.
- Cohen PR, Grossman ME, Almeida L, Kurzrok R. Tripe palms and malignancy. J Clin Oncol. 1989;7:669-78.
- Colaco SM, Miller T, Ruben BS, Fogarty PF, Fox LP. IgM lambda paraproteinemia with associated cutaneous lymphoplasmacytic infiltrate in a patient who meets diagnostic criteria for POEMS syndrome. J Am Acad Dermatol. 2008;58:671-5.
- Czyzyk-Krzeska MF, McCormack FX. Birt-Hogg-Dubé syndrome. Fam Cancer. 2013;12:355-6.
- Dawn G, Wainwright NJ. Association between subacute cutaneous lupus erythematosus and epidermoid carcinoma of the lung: a paraneoplastic phenomenon? Clin Exp Dermatol. 2002;27:717-8.
- Dey D, Kenu E, Isenberg DA. Cancer complicating systemic lupus erythematosus:a dichotomy emerging from a nested case-control study. Lupus. 2013;22:919-27.
- Dourmishev LA, Draganov PV. Paraneoplastic dermatological manifestation of gastrointestinal malignancies. World J Gastroenterol. 2009;15: 4372-9.
- Escribano L, Akin C, Castells M, Orfao A, Metcalfe DD. Mstocytosis: current concepts in diagnosis and treatment. Ann Hematol. 2002;81:677-90.
- Gorovoy IR, McSorley J, Gorovoy JB. Pancreatic paniculitis secondary to acinar cell carcinoma of the páncreas. Cutis. 2013;91:186-90.
- Janniger EJ, Schwartz RA. Florid cutaneous papillomatosis. J Surg Oncol. 2010;102:709-12.
- Kalin A, Merideth MA, Regier DS, Blumenthal GM, Dennis PA, Stratton P. Management of reproductive health in Cowden syndrome complicated by endometrial polyps and breast cancer. Obstet Gynecol. 2013;121(2Pt-2Suppl1):461-4
- Kaminsky A. Eritemas figurados. Actas Dermosifilogr. 2009;100Suppl2: 88-109.
- Kleyn CE, Lai-Cheong JE, Bell HK. Cutaneous manifestations of internal malignancy: diagnosis and management. Am J Clin Der-matol. 2006;7:71-84.
- Kourelis TV, Gertz M, Zent C, Lacy M, Kyle R, Kapoor P. Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma. Am J Hematol. 2013;88:375-8.
- Leger S, Picard D, Ingen-Housz-Oro S, Arnault JP, Aubin F, Carsuzaa F. Prognostic factors of paraneoplastic pemphigus. Arch Dermatol 2012;148:1165-72.
- Leon-Mateos A, Ginarte M, León L, Toribio J. Reticular erythematous mucinosis (REM) with telangiectasias associated with essential thrombocytosis and lung carcinoma. Eur J Dermatol. 2005;15:179-81.
- Metcalfe DD. Differential diagnosis of the patient with unexplained flushing/anaphylaxis. Allergy Asthma Proc. 2000;21:21-4.
- Moore RL, Devere TS. Epidermal manifestations of internal malignancy. Dermatol Clin. 2008;26:17-29.
- Nicol C, Quereux G, Renaut JJ, Renac F, Dreno B. Paraneoplastic multicentric reticulohistiocytosis. Ann Dermatol Venereol. 2011;138:405-8.
- Paydas S. Sweet’s syndrome: a revisit for hematologist and oncologist. Crit Rev Oncol Hematol. 2013;86:85-95.
- Roberts ME, Riegert-Johnson DL, Thomas BC, Thomas CS, Heckman MG, Krishna M. Screening for Muir-Torre syndrome using mismatch repair protein immunohistochemistry of sebaceous neoplasms. J Genet Couns. 2013;22:393-405.
- Santos-Silva AR, Correa MB, Vargas PA, Almeida OP, Lopes MA. Bazex syndrome (acrokeratosis paraneoplastica) diagnosed in a patient with oral persistent ulcerations. Head Neck Pathol. 2010;4:312-7.
- Shirdel A, Yazdanpanah MJ, Pezeshkpoor F, Kalantary MR, Soleimani M. Diffuse normolipaemic plane xanthomatosis associated with adult T-cell lymphoma/leukaemia. J Eur Acad Dermatol Venereol. 2008;22: 1252-3.
- Solans-Laqué R, Bosch-Gil JA, Pérez-Bocanegra C, Selva-O’Callaghan A, Simeón-Aznar CP, Vilardell-Tarres M. Paraneoplastic vasculitis in patients with solid tumors: report of 15 cases. J Rheumatol. 2008;35:294-304.
- Talsania N, Harwood CA, Piras D, Cerio R. Paraneoplastic acanthosis nigricans: the importance of exhaustive and repeated malignancy screening. Dermatol Online J. 2010;15-16:8.
- Tcherney G, Wollina U. Sarcoidosis, cancer and molecular mimicry. Int J Immunopathol Pharmacol. 2013;26:753-5.
- Thrumurthy SG, Anuruddha AH, De Zoysa MI, Samarasekera DN. Unexpected outcome from Trousseau syndrome. BMC Surg. 2011; 11:1.
- Tseng HC, Liu CT, Ho JC, Lin SH. Necrolytic migratory erythema and glucagonoma rising from pancreatic head. Pancreatology. 2013;13:455-7.
- Ungprasert P, Leephon N, Hosiriluck N, Chaiwatcharayut W, Ammannagari N, Raddatz DA. Clinical features of inflammatory myopathies and their association with malignancy: a systemic review in Asian population. ISRN Rheumatol. 2013;2013:509354.
- Von Stempel C, Perks C, Corcoran J, Grayez J. Cardiorespiratory failure secondary to ectopic Cushing’s syndrome as the index presentation of small cell lung cancer. BMJ Case Rep. En prensa 2013.
- Yuste M, Santos JC, Sánchez-Estella J, Alonso MT. Edema facial en Síndrome de Vena Cava superior: descripción de dos casos. Med Cutan Iber Lat Am. 2004;32:254-8.