Complicaciones gástricas de tratamientos farmacológicos

  1. I. Gil-Aldea 1
  2. J.R. Azanza Perea 2
  1. 1 Navarrabiomed. Fundación Miguel Servet. Servicio Navarro de Salud-Osasunbidea. Pamplona.
  2. 2 Clínica Universitaria de Navarra
    info

    Clínica Universitaria de Navarra

    Pamplona, España

    ROR https://ror.org/03phm3r45

Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Año de publicación: 2016

Título del ejemplar: Enfermedades del aparato digestivo (III): Patología gastroduodenal (II)

Serie: 12

Número: 3

Páginas: 137-142

Tipo: Artículo

DOI: 10.1016/J.MED.2016.02.004 DIALNET GOOGLE SCHOLAR

Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado

Objetivos de desarrollo sostenible

Resumen

Introduction Gastric drug complications are one of the more adverse effects prominent and most clinically relevant, NSAIDs being the main causes. Pathogenesis The damage level gastric mucosa can be presented in different ways, being the fundamental mechanism inhibition of prostaglandin synthesis. Risk factor's There are several risk factors, dependent and independent, which allow to stratify patients according to their risk and, accordingly, take preventive measures. Prevention and treatment Among these measures, coadministration with NSAIDs proton-pump inhibitor or administration of COX-2 inhibitor have proven to be effective measures in randomized studies. However, you should evaluate other preventive and therapeutic administration of NSAIDs alternatives, mainly due to the risk. This associated cardiovascular drug group and, in particular, selective inhibitors COX-2.

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Fuente de los datos: Dialnet