Hipotiroidismo

  1. J. Pineda 1
  2. J.C. Galofré 2
  3. M. Toni 3
  4. E. Anda 1
  1. 1 Complejo Hospitalario de Navarra. Pamplona. Navarra. España
  2. 2 Clínica Universidad de Navarra. Pamplona. Navarra. España
  3. 3 Instituto de Investigación Sanitaria de Navarra (IdiSNA). Pamplona. España
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Issue Title: Enfermedades endocrinológicas y metabólicas (I) Patología del tiroides

Series: 12

Issue: 13

Pages: 722-730

Type: Article

DOI: 10.1016/J.MED.2016.06.002 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Sustainable development goals

Abstract

Introduccion Hypothyroidism is defined as the clinical condition resulting from the lack of action of thyroid hormones in different tissues. Aetiology In the majority of cases is due to a defect in the thyroid gland (primary hypothyroidism). The most common cause worldwide is iodine deficiency although in iodine-sufficient areas chronic the leading cause is autoimmune thyroiditis. Epidemiology Hypothyroidism is the most frequent thyroid dysfunction, especially subclinical hypothyroidism, which can reach 10% prevalence in the elderly. Clinical manifestations and diagnosis Clinical manifestations are not specific, so the diagnosis is based on laboratory tests (mainly TSH determination). Treatment Levothyroxine remains the treatment of choice. The deleterious health effects and the benefits of levothyroxine replacement therapy remain controversial in subclinical hypothyroidism. There is consensus to start treatment if TSH levels are greater than 10 UI/l or in certain clinical situations.

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