Corrección de atenuación en equipos PET-RMcomparación de métodos mediante simulación Monte Carlo

  1. José Pablo Cabello García 1
  2. Roser Sala-Llonch 2
  3. Raúl Tudela Fernández 3
  4. Domènec Ros Puig 2
  5. Javier Pavía Segura 1
  6. Aida Niñerola Baizán 1
  1. 1 Hospital Clínic de Barcelona, España
  2. 2 Universidad de Barcelona, España
  3. 3 Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Bacelona, España
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Revista:
Revista de Física Médica

ISSN: 1576-6632

Año de publicación: 2020

Volumen: 21

Número: 2

Páginas: 43-52

Tipo: Artículo

DOI: 10.37004/SEFM/2020.21.2.004 DIALNET GOOGLE SCHOLAR lock_openAcceso abierto editor

Otras publicaciones en: Revista de Física Médica

Resumen

La visualización y cuantificación adecuadas de una imagen de tomografía por emisión de positrones (PET) requiere la corrección por la atenuación que sufren os fotones al atravesar el medio. En un equipo híbrido que combina PET con resonancia magnética (RM), la señal de RM no puede convertirse en valores de atenuación de forma directa. En este trabajo se analizaron dos métodos de estimación del mapa de atenuación, el primero basado en segmentación de la imagen RM y el segundo en un promedio de imágenes de tomografía computarizada (TC) a partir de múltiples sujetos. El estudio se realizó utilizando imágenes PET obtenidas mediante simulación Monte Carlo y el parámetro cuantitativo evaluado fue el valor de captación estandarizado relativo (SUVr) tomando como región de referencia el cerebelo. La comparación de los resultados obtenidos con cada método con los correspondientes al utilizar la imagen TC propia de cada paciente (considerado como gold standard) indica que: 1) ambos métodos pierden exactitud en la zona próxima al tejido óseo, 2) en un análisis de SUVr por regiones, el método que utiliza segmentación a partir de la imagen de RM da mejores resultados con diferencias relativas máximas en torno al 5% frente al gold standard.

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Fuente de los datos: Dialnet