Infecciones en el paciente inmunocomprometido (I). Paciente con tratamiento esteroideo y otros inmunosupresores. Paciente neutropénico
- Falcón Abad, R. 1
- Íñigo Pestaña, M. 1
- Pérez García, A. 1
- 1 Servicio de Microbiología Clínica y Parasitología, Clínica Universidad de Navarra, Madrid, España
ISSN: 0304-5412
Año de publicación: 2022
Título del ejemplar: Enfermedades infecciosas (VIII)
Serie: 13
Número: 56
Páginas: 3277-3287
Tipo: Artículo
Otras publicaciones en: Medicine: Programa de Formación Médica Continuada Acreditado
Resumen
Infections represent one of the main causes of morbidity and mortality in immunosuppressed patients. Prolonged, profound neutropenia is one of the most important risk factors of sepsis and associated mortality. Fever may be the only clinical symptom these patients manifest; it is considered a medical emergency. Glucocorticoids act on various levels of inflammatory and immunological processes, facilitating opportunistic infections. Biological therapies are becoming more and more varied, with effects that remain to be studied. Therefore, the indications must be updated and reviewed periodically. A rapid diagnosis that guides effective treatment is crucial for avoiding infectious complications in these patients. The emergence of multidrug-resistant microorganisms is a challenge to the treatment approach to patients with febrile neutropenia.
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