Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

  1. Green, A.C.
  2. Marttila, P.
  3. Kiweler, N.
  4. Chalkiadaki, C.
  5. Wiita, E.
  6. Cookson, V.
  7. Lesur, A.
  8. Eiden, K.
  9. Bernardin, F.
  10. Vallin, K.S.A.
  11. Borhade, S.
  12. Long, M.
  13. Ghahe, E.K.
  14. Jiménez-Alonso, J.J.
  15. Jemth, A.-S.
  16. Loseva, O.
  17. Mortusewicz, O.
  18. Meyers, M.
  19. Viry, E.
  20. Johansson, A.I.
  21. Hodek, O.
  22. Homan, E.
  23. Bonagas, N.
  24. Ramos, L.
  25. Sandberg, L.
  26. Frödin, M.
  27. Moussay, E.
  28. Slipicevic, A.
  29. Letellier, E.
  30. Paggetti, J.
  31. Sørensen, C.S.
  32. Helleday, T.
  33. Henriksson, M.
  34. Meiser, J.
  35. Show all authors +
Journal:
Nature Metabolism

ISSN: 2522-5812

Year of publication: 2023

Volume: 5

Issue: 4

Pages: 642-659

Type: Article

DOI: 10.1038/S42255-023-00771-5 GOOGLE SCHOLAR lock_openOpen access editor