Infecciones por otros bacilos Gram negativosgrupo HACEK

  1. Leiva, J.
  2. Reina, G.
  3. Fernández-Alonso, M.
  4. del Pozo, J.L.
Zeitschrift:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Datum der Publikation: 2018

Titel der Ausgabe: Enfermedades infecciosas (II): Infecciones por bacilos Gram negativos

Serie: 12

Nummer: 50

Seiten: 2963-2971

Art: Artikel

DOI: 10.1016/J.MED.2018.02.013 DIALNET GOOGLE SCHOLAR

Andere Publikationen in: Medicine: Programa de Formación Médica Continuada Acreditado

Zusammenfassung

Introduction The HACEK group (Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, Kingella) includes slow-growing gram-negative bacteria that form part of the microbiota of the upper respiratory and genitourinary tracts of humans and animals. Clinical manifestations These are the slow-growing, gram-negative bacilli that most frequently cause infections in human beings, and can give rise to infections in any location, but fundamentally the skin and soft tissues, and cause bacteraemia and endocarditis. Diagnosis They are nutritionally demanding bacteria and for visible colonies to develop require blood agar or chocolate agar, an aerobic atmosphere, generally CO2 rich and incubation of at least 42hours. They are difficult to identify phenotypically as a species and it is not always possible to do so, even using automated systems. However molecular and proteomic techniques have resulted in increased identification and an awareness of their role in human infectious pathology. Treatment There is limited data on their sensitivity to antimicrobial agents, although from the existing data it is known that amoxicillin-clavulanic acid, second and third generation cephalosporins and fluoroquinolones generally act against them.

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