Evaluación Neurocognitiva y Flujo Sanguíneo Cerebral Regional en Pacientes con Deterioro Cognitivo Leve
- Ginarte Arias, Yurelis
- Férnandez García, Yuriem
- Sanchéz Catasús, Carlos
- López Pérez, Mary Blanca
- Samper Noa, Juan
- Almunia Aguilar, Belkis
ISSN: 0124-1265
Datum der Publikation: 2010
Ausgabe: 10
Nummer: 1
Seiten: 49-60
Art: Artikel
Andere Publikationen in: Revista Neuropsicología, Neuropsiquiatría y Neurociencias
Zusammenfassung
Introduction. Mild Cognitive Impairment (MCI) is a research field that demandes the combination of different methods to study brains functions. In this perspective, neuropsychologicals tests and functional neurimages by SPECT (Single Photon Emission Computed Tomography) can be very useful. The objective of the study was to compare the performance in neurocognitives tests between a group of subjects with MCI and a control group, to characterize the differences in regional cerebral blood flow through SPECT between both groups and to determine if there is any association between the neurocognitives tests that show less performance in the MCI group and the brain regions that well be a hypoperfusion in this patients. Method. The sample consisted of a control group of 10 cognitively normal subjects and a group of 10 patients with the MCI. Standardized clinical instruments, neurocognitive tests and Nuclear Magnetic Resonance (RMN) and SPECT scans were applied to both groups. Mann Whitney test and Spearman test (p<0,05) was used to statistic analysis. Results and Conclusions. The MCI group showed less performance than the control group in tests of short time memory, episodic memory, attention and executive functions. The blood flow of some temporal, limbic and parietal regions were less in these patients too, who showed a greater association with episodic memory.