Tumor de células yuxtaglomerularesreporte de un caso

  1. Irene Ruiz Adelantado
  2. Clara Sáez Ibarra
  3. Laura Noguera Alonso
  4. Lorenzo Alarcón García
Journal:
Revista Sanitaria de Investigación

ISSN: 2660-7085

Year of publication: 2024

Volume: 5

Issue: 5

Type: Article

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Abstract

Introduction: Juxtaglomerular cell tumor is a renal tumor of mesenchymal origin that occurs in young adults and often presents with a characteristic clinical picture of refractory arterial hypertension, hypokalemia, and increased serum renin levels. Case report: We present a case of a 46-year-old male with a history of arterial hypertension and hypokalemia, who is being treated pharmacologically with four antihypertensive drugs. Radiological evaluations identified a 2 cm renal lesion, which was surgically intervened and diagnosed as a juxtaglomerular cell tumor. Following the intervention, progressive normalization of analytical values and blood pressure, along with an improvement in clinical symptoms, were observed. Discussion: These tumors have morphological and immunohistochemical characteristics that allow for a definitive diagnosis. Although some cases are treated with radioablation, surgical treatment remains the gold standard. It has been subclassified into three groups based on lesion functionality. Some articles describe cases with histological features of malignancy (necrosis, atypia, and high proliferative index), and even images of angioinvasion, which require closer monitoring, as cases of recurrence and metastasis have been reported.

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