Severe colon ischemia in patients with severe coronavirus-19 (COVID-19)

  1. Almeida Vargas, Ana 1
  2. Valentí, Víctor 123
  3. Sánchez Justicia, Carlos 1
  4. Martínez Regueira, Fernando 1
  5. Martí Cruchaga, Pablo 1
  6. Luján Colás, Juan 1
  7. Aliseda Jover, Daniel 1
  8. Esteban Gordillo, Sara 1
  9. Cienfuegos, Javier A. 123
  10. Rotellar Sastre, Fernando 1
  1. 1 Clínica Universitaria de Navarra
    info

    Clínica Universitaria de Navarra

    Pamplona, España

    ROR https://ror.org/03phm3r45

  2. 2 Instituto de Investigación Sanitaria de Navarra
    info

    Instituto de Investigación Sanitaria de Navarra

    Pamplona, España

  3. 3 Instituto de Salud Carlos III
    info

    Instituto de Salud Carlos III

    Madrid, España

    ROR https://ror.org/00ca2c886

Aldizkaria:
Revista Española de Enfermedades Digestivas

ISSN: 1130-0108

Argitalpen urtea: 2020

Alea: 112

Zenbakia: 10

Orrialdeak: 784 - 787

Mota: Artikulua

DOI: 10.17235/REED.2020.7329/2020 PMID: 32954769 SCOPUS: 2-s2.0-85091981452 WoS: WOS:000580401700008 GOOGLE SCHOLAR lock_openSarbide irekia editor

Beste argitalpen batzuk: Revista Española de Enfermedades Digestivas

Laburpena

COVID-19 is associated with severe coagulopathy. We present three cases of colonic ischemia that can be attributed to the hypercoagulable state related with SARS-CoV2 and disseminated intravascular coagulation. Three males aged 76, 68 and 56 with respiratory distress presented episodes of rectal bleeding, abdominal distension and signs of peritoneal irritation. Endoscopy (case 1) and computed tomography angiography revealed colonic ischemia. One patient (case 2) in which a computed tomography (CT) scan showed perforation of the gangrenous cecum underwent surgery. D-dimer levels were markedly increased (2,170, 2,100 and 7,360 ng/ml) in all three patients. All three patients died shortly after diagnosis.

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