Treatment of graft-versus-host disease with mesenchymal cells as a complication of a liver transplantation

  1. Mora, Lorena 1
  2. Alegre, Félix 1
  3. Rifón, José Juan 12
  4. Martí, Pablo 12
  5. Herrero, José Ignacio 123
  1. 1 Clínica Universitaria de Navarra
    info

    Clínica Universitaria de Navarra

    Pamplona, España

    ROR https://ror.org/03phm3r45

  2. 2 Instituto de Investigación Sanitaria de Navarra
    info

    Instituto de Investigación Sanitaria de Navarra

    Pamplona, España

  3. 3 Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas
    info

    Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas

    Madrid, España

    ROR https://ror.org/03cn6tr16

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Journal:
Revista Española de Enfermedades Digestivas

ISSN: 1130-0108

Year of publication: 2018

Volume: 110

Issue: 11

Pages: 734 - 736

Type: Article

DOI: 10.17235/REED.2018.5672/2018 PMID: 30284904 SCOPUS: 2-s2.0-85056286867 WoS: WOS:000448718900010 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Revista Española de Enfermedades Digestivas

Abstract

We present the case of a liver transplant (LT) recipient donor who developed graft versus host disease (GVHD).The main features were cutaneous rash, diarrhea and pancytopenia. Mesenchymal cells were administered as part of the treatment. This is the first case of a patient with GVHD after LT reported to date. Despite the treatment, there was no improvement in aplasia or gastrointestinal symptoms and the patient died due to a disseminated infection.

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