Inmunomodulación y Microambiente Tumoral
ITAM
Centro de Investigación Biomédica en Red de Cáncer
Madrid, EspañaPublicacions en col·laboració amb investigadors/es de Centro de Investigación Biomédica en Red de Cáncer (17)
2024
-
Tethered IL15-IL15Rα augments antitumor activity of CD19 CAR-T cells but displays long-term toxicity in an immunocompetent lymphoma mouse model
Journal for immunotherapy of cancer, Vol. 12, Núm. 7
2023
-
FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma
Molecular Therapy, Vol. 31, Núm. 1, pp. 48-65
-
Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia
Frontiers in Immunology, Vol. 14
-
PTEN Loss Confers Resistance to Anti–PD-1 Therapy in Non–Small Cell Lung Cancer by Increasing Tumor Infiltration of Regulatory T Cells
Cancer Research, Vol. 83, Núm. 15, pp. 2513-2526
-
Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer
EMBO Reports, Vol. 24, Núm. 8
-
The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
EMBO Reports, Vol. 24, Núm. 5
2022
-
CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome
Science Advances, Vol. 8, Núm. 39
-
Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination
Frontiers in Immunology, Vol. 13
-
Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
Frontiers in Immunology, Vol. 13
2021
-
Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential
Frontiers in Immunology, Vol. 12
-
Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses
Emerging Microbes and Infections, Vol. 10, Núm. 1, pp. 1931-1946
-
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes
British Journal of Cancer, Vol. 124, Núm. 6, pp. 1138-1149
2020
-
Id1 and pd-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-l1 expression and tumor infiltrating CD8+ T cells
Cancers, Vol. 12, Núm. 11, pp. 1-22
-
Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
2019
-
Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses
Molecular Therapy, Vol. 27, Núm. 11, pp. 1892-1905
-
Treatment of experimental autoimmune encephalomyelitis by sustained delivery of low-dose IFN-a
Journal of Immunology, Vol. 203, Núm. 3, pp. 696-704
2017
-
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis
Cancer Discovery, Vol. 7, Núm. 7, pp. 694-703