Terapia Génica en Enfermedad de Parkinson
PARKBA SAL
José Luis
Labandeira-García
José Luis Labandeira-García-rekin lankidetzan egindako argitalpenak (28)
2023
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A randomized clinical trial of candesartan for cognitive impairment in Parkinson's disease
Parkinsonism and Related Disorders, Vol. 110
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AT1 receptor autoantibodies mediate effects of metabolic syndrome on dopaminergic vulnerability
Brain, Behavior, and Immunity, Vol. 108, pp. 255-268
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Boolean analysis shows a high proportion of dopamine D2 receptors interacting with adenosine A2A receptors in striatal medium spiny neurons of mouse and non-human primate models of Parkinson's disease
Neurobiology of Disease, Vol. 188
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Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates
Brain : a journal of neurology, Vol. 146, Núm. 12, pp. 5000-5014
2021
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An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria
Redox Biology, Vol. 46
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Glucocerebrosidase gene therapy induces alpha-synuclein clearance and neuroprotection of midbrain dopaminergic neurons in mice and macaques
International Journal of Molecular Sciences, Vol. 22, Núm. 9
2018
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Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death
Neurotherapeutics, Vol. 15, Núm. 4, pp. 1063-1081
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Gene therapy approaches in the non-human primate model of Parkinson’s disease
Journal of Neural Transmission, Vol. 125, Núm. 3, pp. 575-589
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Glucocerebrosidase expression patterns in the non-human primate brain
Brain Structure and Function, Vol. 223, Núm. 1, pp. 343-355
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Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans
Molecular Neurobiology, Vol. 55, Núm. 7, pp. 5847-5867
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Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia
Brain, Behavior, and Immunity, Vol. 67, pp. 139-151
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Usefulness of identifying g-protein-coupled receptor dimers for diagnosis and therapy of neurodegenerative diseases and of gliomas
Histology and Histopathology, Vol. 33, Núm. 9, pp. 909-917
2017
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Brain renin-angiotensin system and microglial polarization: Implications for aging and neurodegeneration
Frontiers in Aging Neuroscience, Vol. 9, Núm. MAY
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Expression of angiotensinogen and receptors for angiotensin and prorenin in the rat and monkey striatal neurons and glial cells
Brain Structure and Function, Vol. 222, Núm. 6, pp. 2559-2571
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Neurochemical evidence supporting dopamine D1–D2 receptor heteromers in the striatum of the long-tailed macaque: changes following dopaminergic manipulation
Brain Structure and Function, Vol. 222, Núm. 4, pp. 1767-1784
2016
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Hints on the Lateralization of Dopamine Binding to D
1
Receptors in Rat Striatum
Molecular Neurobiology, Vol. 53, Núm. 8, pp. 5436-5445
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Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
Cell Death and Disease, Vol. 7, Núm. 10
2015
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Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats
Neurobiology of Aging, Vol. 36, Núm. 2, pp. 1194-1208
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Detection of cannabinoid receptors CB1 and CB2 within basal ganglia output neurons in macaques: changes following experimental parkinsonism
Brain Structure and Function, Vol. 220, Núm. 5, pp. 2721-2738
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Dopamine D2 and angiotensin II type 1 receptors form functional heteromers in rat striatum
Biochemical Pharmacology, Vol. 96, Núm. 2, pp. 131-142