Estrategias Combinadas en Inmunoterapia Traslacional
ITC
Yale School of Medicine
New Haven, Estados UnidosPublicaciones en colaboración con investigadores/as de Yale School of Medicine (27)
2024
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Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities
Journal for immunotherapy of cancer, Vol. 12, Núm. 5
2022
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Nivolumab plus rucaparib for metastatic castration-resistant prostate cancer: results from the phase 2 CheckMate 9KD trial
Journal for immunotherapy of cancer, Vol. 10, Núm. 8
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Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies
Journal for immunotherapy of cancer, Vol. 10, Núm. 3
2021
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A burned-out cd8+ t-cell subset expands in the tumor microenvironment and curbs cancer immunotherapy
Cancer Discovery, Vol. 11, Núm. 7, pp. 1700-1715
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Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8
Journal of Pathology, Vol. 255, Núm. 2, pp. 190-201
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IL8, neutrophils, and NETs in a collusion against cancer immunity and immunotherapy
Clinical Cancer Research, Vol. 27, Núm. 9, pp. 2383-2393
2020
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Immunity, Vol. 52, Núm. 5, pp. 856-871.e8
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Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors
Nature Medicine, Vol. 26, Núm. 5, pp. 688-692
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Immunological impact of cell death signaling driven by radiation on the tumor microenvironment
Nature Immunology, Vol. 21, Núm. 2, pp. 120-134
2019
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Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
Nature Medicine, Vol. 25, Núm. 3, pp. 470-476
2018
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Combined immunotherapy encompassing intratumoral poly-ICLC, dendritic-cell vaccination and radiotherapy in advanced cancer patients
Annals of Oncology, Vol. 29, Núm. 5, pp. 1312-1319
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Immunodivergence in Metastatic Colorectal Cancer
Cancer Cell
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Immunotherapy targeting 4-1BB: Mechanistic rationale, clinical results, and future strategies
Blood, Vol. 131, Núm. 1, pp. 49-57
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Introducing a new series: Immunotherapy facts and hopes
Clinical Cancer Research
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Liquid Biopsy: From Basic Research to Clinical Practice
Advances in Clinical Chemistry (Academic Press Inc.), pp. 73-119
2017
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Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients
Annals of Oncology, Vol. 28, Núm. 8, pp. 1988-1995
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Impaired HLA class I antigen processing and presentation as a mechanism of acquired resistance to immune checkpoint inhibitors in lung cancer
Cancer Discovery, Vol. 7, Núm. 12, pp. 1420-1435
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Interleukin-8 in cancer pathogenesis, treatment and follow-up
Cancer Treatment Reviews, Vol. 60, pp. 24-31
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Predictors of responses to immune checkpoint blockade in advanced melanoma
Nature Communications, Vol. 8, Núm. 1
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Strategies to design clinical studies to identify predictive biomarkers in cancer research
Cancer Treatment Reviews, Vol. 53, pp. 79-97