Publications by the researcher in collaboration with Ignacio Melero (8)

2015

  1. Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression

    Gene Therapy, Vol. 22, Núm. 11, pp. 856-865

2014

  1. Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus

    PLoS ONE, Vol. 9, Núm. 1

  2. Liver Gene Therapy Approaches for Acute Intermittent Porphyria: Metabolic Correction and Immunological Hurdles

    HANDBOOK OF PORPHYRIN SCIENCE WITH APPLICATIONS TO CHEMISTRY, PHYSICS, MATERIALS SCIENCE, ENGINEERING, BIOLOGY AND MEDICINE, VOL 29: PORPHYRIAS AND SIDEROBLASTIC ANEMIAS (WORLD SCIENTIFIC PUBL CO PTE LTD), pp. 415-450

2012

  1. Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.

    Journal of translational medicine, Vol. 10, pp. 122

2010

  1. Immunology and gene therapy: Shoulder to shoulder into the fray

    Molecular Therapy

  2. Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates

    Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765

  3. Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria

    Journal of Hepatology, Vol. 52, Núm. 3, pp. 417-424

2009

  1. PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector

    Gene Therapy, Vol. 16, Núm. 1, pp. 136-141