Hepatología: Metabolismo, Epigenética y Carcinogénesis
METACAN
Hospital Universitario de Donostia
San Sebastián, EspañaPublicaciones en colaboración con investigadores/as de Hospital Universitario de Donostia (26)
2024
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Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1
JHEP Reports, Vol. 6, Núm. 1
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SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
Cell Reports, Vol. 43, Núm. 3
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Sensitizing cholangiocarcinoma to chemotherapy by inhibition of the drug-export pump MRP3
Biomedicine and Pharmacotherapy, Vol. 180
2022
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Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions
Gut, Vol. 71, Núm. 8, pp. 1669-1683
2021
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Correction: Current and novel therapeutic opportunities for systemic therapy in biliary cancer (British Journal of Cancer, (2020), 123, 7, (1047-1059), 10.1038/s41416-020-0987-3)
British Journal of Cancer
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Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma
Hepatology, Vol. 73, Núm. 6, pp. 2380-2396
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High prevalence of insulin resistance in asymptomatic patients with acute intermittent porphyria and liver-targeted insulin as a novel therapeutic approach
Biomedicines, Vol. 9, Núm. 3, pp. 1-18
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Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis
Molecular Metabolism, Vol. 53
2020
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A novel serum metabolomic profile for the differential diagnosis of distal cholangiocarcinoma and pancreatic ductal adenocarcinoma
Cancers, Vol. 12, Núm. 6
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Current and novel therapeutic opportunities for systemic therapy in biliary cancer
British Journal of Cancer, Vol. 123, Núm. 7, pp. 1047-1059
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Dual pharmacological targeting of hdacs and pde5 inhibits liver disease progression in a mouse model of biliary inflammation and fibrosis
Cancers, Vol. 12, Núm. 12, pp. 1-27
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Multi‐omics integration highlights the role of ubiquitination in ccl4‐induced liver fibrosis
International Journal of Molecular Sciences, Vol. 21, Núm. 23, pp. 1-19
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Pilot multi-omic analysis of human bile from benign and malignant biliary strictures: A machine-learning approach
Cancers, Vol. 12, Núm. 6, pp. 1-30
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Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets
Liver International, Vol. 40, Núm. 7, pp. 1670-1685
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S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1866, Núm. 11
2019
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Causes of hOCT1-Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor-Selective Gene Therapy
Hepatology, Vol. 70, Núm. 4, pp. 1246-1261
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
Gut, Vol. 68, Núm. 3, pp. 533-546
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
EBioMedicine, Vol. 40, pp. 406-421
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Serum Metabolites as Diagnostic Biomarkers for Cholangiocarcinoma, Hepatocellular Carcinoma, and Primary Sclerosing Cholangitis
Hepatology, Vol. 70, Núm. 2, pp. 547-562