Juan José
Lasarte Sagastibelza
Catedrático de Universidad
Publikationen, an denen er mitarbeitet Juan José Lasarte Sagastibelza (28)
2024
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Tethered IL15-IL15Rα augments antitumor activity of CD19 CAR-T cells but displays long-term toxicity in an immunocompetent lymphoma mouse model
Journal for immunotherapy of cancer, Vol. 12, Núm. 7
2023
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FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma
Molecular Therapy, Vol. 31, Núm. 1, pp. 48-65
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Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia
Frontiers in Immunology, Vol. 14
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Plasma fractalkine contributes to systemic myeloid diversity and PD-L1/PD-1 blockade in lung cancer
EMBO Reports, Vol. 24, Núm. 8
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
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The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
EMBO Reports, Vol. 24, Núm. 5
2022
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CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome
Science Advances, Vol. 8, Núm. 39
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CAR-T Cells for the Treatment of Lung Cancer
Life, Vol. 12, Núm. 4
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Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
Frontiers in Immunology, Vol. 13
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Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy
OncoImmunology, Vol. 11, Núm. 1
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Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 8
2021
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Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential
Frontiers in Immunology, Vol. 12
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Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses
Emerging Microbes and Infections, Vol. 10, Núm. 1, pp. 1931-1946
2020
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Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
Journal for ImmunoTherapy of Cancer, Vol. 8, Núm. 1
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Re: Inhibition of a G9a/DNMT Network Triggers Immune-Mediated Bladder Cancer Regression
Journal of Urology
2019
2017
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
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Identification of LAG3 high affinity aptamers by HT-SELEX and Conserved Motif Accumulation (CMA)
PLoS ONE, Vol. 12, Núm. 9
2016
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MRP1-CD28 bi-specific oligonucleotide aptamers: Target costimulation to drug-resistant melanoma cancer stem cells
Oncotarget, Vol. 7, Núm. 17, pp. 23182-23196
2009
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Induction of multiepitopic and long-lasting immune responses against tumour antigens by immunization with peptides, DNA and recombinant adenoviruses expressing minigenes
Scandinavian Journal of Immunology, Vol. 69, Núm. 2, pp. 80-89