Hematología Traslacional
Kiel University
Kiel, AlemaniaPublikationen in Zusammenarbeit mit Forschern von Kiel University (21)
2016
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Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage
Cancer Cell, Vol. 30, Núm. 5, pp. 806-821
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Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics
Nature Communications, Vol. 7
2015
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Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers
Genome Research, Vol. 25, Núm. 4, pp. 478-487
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Whole-genome fingerprint of the DNA methylome during human B cell differentiation
Nature Genetics, Vol. 47, Núm. 7, pp. 746-756
2014
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Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
Journal of Hematology and Oncology, Vol. 7, Núm. 1
2013
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Landscape of somatic mutations and clonal evolution in mantle cell lymphoma
Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Núm. 45, pp. 18250-18255
2012
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A DNA methylation fingerprint of 1628 human samples
Genome Research, Vol. 22, Núm. 2, pp. 407-419
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Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 26, pp. 10534-10539
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Molecular subsets of mantle cell lymphoma defined by the IGHV mutational status and SOX11 expression have distinct biologic and clinical features
Cancer Research, Vol. 72, Núm. 20, pp. 5307-5316
2011
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A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma
Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Núm. 30, pp. 12461-12466
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Epigenetic activation of SOX11 in Lymphoid Neoplasms by Histone modifications
PLoS ONE, Vol. 6, Núm. 6
2010
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Lymphoma stem cells: Enough evidence to support their existence?
Haematologica, Vol. 95, Núm. 2, pp. 293-302
2009
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A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms
PLoS ONE, Vol. 4, Núm. 9
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Biallelic inactivation of TRAF3 in a subset of B-cell lymphomas with interstitial del(14)(q24.1q32.33)
Leukemia, Vol. 23, Núm. 11, pp. 2153-2155
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Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
Blood, Vol. 114, Núm. 13, pp. 2688-2698
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Epigenetic signatures associated with different levels of differentiation potential in human stem cells
PLoS ONE, Vol. 4, Núm. 11
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Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia
Cancer Research, Vol. 69, Núm. 10, pp. 4443-4453
2003
2001
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Amplification of ERBB2, RARA, and TOP2A genes in a myelodysplastic syndrome transforming to acute myeloid leukemia
Cancer Genetics and Cytogenetics, Vol. 127, Núm. 2, pp. 174-176
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Cytogenetic and molecular characterization of a patient with simultaneous B-cell chronic lymphocytic leukemia and peripheral T-cell lymphoma
American Journal of Hematology, Vol. 68, Núm. 4, pp. 276-279