Hematología Traslacional
Northwestern University
Evanston, Estados UnidosPublikationen in Zusammenarbeit mit Forschern von Northwestern University (7)
2017
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Global position paper on cardiovascular regenerative medicine
European Heart Journal
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UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition
Cell Reports, Vol. 21, Núm. 3, pp. 628-640
2015
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The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Nature Medicine, Vol. 21, Núm. 10, pp. 1199-1208
2014
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Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome through Global and Focal Changes in H3K36 and H3K27 Methylation
PLoS Genetics, Vol. 10, Núm. 9
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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies
Leukemia
2013
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EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Cancer Cell, Vol. 23, Núm. 5, pp. 677-692
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The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer
Oncogene, Vol. 32, Núm. 23, pp. 2882-2890