Linfomas
GLUN
Xabier
Aguirre Ena
Profesional Investigador
Publicaciones en las que colabora con Xabier Aguirre Ena (19)
2023
-
Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
2021
-
Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
2018
-
Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6546-6573
-
Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
2017
2016
2012
-
Epigenetic regulation of miRNA genes in acute leukemia
Leukemia, Vol. 26, Núm. 3, pp. 395-403
-
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 26, pp. 10534-10539
-
High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma
British Journal of Haematology, Vol. 158, Núm. 6, pp. 712-726
-
Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia
Leukemia, Vol. 26, Núm. 7, pp. 1517-1526
2011
-
Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia
Haematologica, Vol. 96, Núm. 10, pp. 1448-1456
-
LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
Haematologica, Vol. 96, Núm. 7, pp. 980-986
2010
-
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma
Blood, Vol. 116, Núm. 14, pp. 2531-2542
2009
-
Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia
European Journal of Cancer, Vol. 45, Núm. 10, pp. 1877-1889
2007
-
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
Blood, Vol. 109, Núm. 1, pp. 271-280
2005
-
Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas
Genes Chromosomes and Cancer, Vol. 43, Núm. 4, pp. 414-423
2003
-
Methylation of CpG dinucleotides and/or CCWGG motifs at the promoter of TP53 correlates with decreased gene expression in a subset of acute lymphoblastic leukemia patients
Oncogene, Vol. 22, Núm. 7, pp. 1070-1072
-
TP53 Is Frequently Altered by Methylation, Mutation, and/or Deletion in Acute Lymphoblastic Leukaemia
Molecular Carcinogenesis, Vol. 38, Núm. 4, pp. 201-208
2002
-
Exon concatenation to increase the efficiency of mutation screening by DGGE
BioTechniques, Vol. 32, Núm. 5, pp. 1064-1070