Oncogenes y Dianas Efectoras
PANCCUN
Karmele
Valencia Leoz
Profesional Investigadora
Publicaciones en las que colabora con Karmele Valencia Leoz (13)
2024
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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation
Molecular Cancer, Vol. 23, Núm. 1
2023
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LAMC2 Regulates Key Transcriptional and Targetable Effectors to Support Pancreatic Cancer Growth
Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 29, Núm. 6, pp. 1137-1154
2022
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Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis
Cancer Letters, Vol. 529, pp. 70-84
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Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
Cancer Discovery, Vol. 12, Núm. 5, pp. 1356-1377
2020
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Liver Kinase B1 (LKB1) Loss Has its p-ERKs: ERK Inactivation as a Vulnerability in NSCLC With LKB1 Mutations
Journal of Thoracic Oncology
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
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The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
Journal of Clinical Investigation, Vol. 130, Núm. 4, pp. 1879-1895
2017
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All for one and FOSL1 for all: FOSL1 at the crossroads of lung and pancreatic cancer driven by mutant KRAS
Molecular and Cellular Oncology, Vol. 4, Núm. 3
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An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
Nature Communications, Vol. 8
2016
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Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis
Journal of Pathology, Vol. 239, Núm. 4, pp. 438-449
2014
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A gene signature of bone metastatic colonization sensitizes for tumor-induced osteolysis and predicts survival in lung cancer
Oncogene, Vol. 33, Núm. 43, pp. 5090-5099
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RHOB influences lung adenocarcinoma metastasis and resistance in a host-sensitive manner
Molecular Oncology, Vol. 8, Núm. 2, pp. 196-206
2011
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Tumor-stromal interactions of the bone microenvironment: In vitro findings and potential in vivo relevance in metastatic lung cancer models
Clinical and Experimental Metastasis, Vol. 28, Núm. 8, pp. 779-791