Iñaki
Etxeberria Ruesta
Publicaciones en las que colabora con Iñaki Etxeberria Ruesta (25)
2023
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Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse models
Oncoimmunology, Vol. 12, Núm. 1, pp. 2147317
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Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity
Cancer immunology research, Vol. 11, Núm. 2, pp. 184-198
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Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
Cell Reports Medicine, Vol. 4, Núm. 4
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mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
Cell Reports Medicine, Vol. 4, Núm. 3
2022
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A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα and IL-1β
Cancer Discovery, Vol. 12, Núm. 9, pp. 2140-2157
2021
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Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, Núm. 26
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CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation
Nature Communications, Vol. 12, Núm. 1
2020
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Immunity, Vol. 52, Núm. 5, pp. 856-871.e8
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Cellular cytotoxicity is a form of immunogenic cell death
Journal for ImmunoTherapy of Cancer, Vol. 8, Núm. 1
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Engineering bionic T cells: signal 1, signal 2, signal 3, reprogramming and the removal of inhibitory mechanisms
Cellular and Molecular Immunology, Vol. 17, Núm. 6, pp. 576-586
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Human CD8 T cells are susceptible to TNF-mediated activation-induced cell death
Theranostics, Vol. 10, Núm. 10, pp. 4481-4489
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New emerging targets in cancer immunotherapy: CD137/4-1BB costimulatory axis
ESMO open, Vol. 4, pp. e000733
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Repurposing infectious disease vaccines for intratumoral immunotherapy
Journal for ImmunoTherapy of Cancer, Vol. 8, Núm. 1
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Repurposing the yellow fever vaccine for intratumoral immunotherapy
EMBO Molecular Medicine, Vol. 12, Núm. 1
2019
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Immunotherapeutic effects of intratumoral nanoplexed poly I:C
Journal for ImmunoTherapy of Cancer, Vol. 7, Núm. 1
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Intratumor Adoptive Transfer of IL-12 mRNA Transiently Engineered Antitumor CD8+ T Cells
Cancer cell, Vol. 36, Núm. 6, pp. 613-629
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Metabolic consequences of T-cell costimulation in anticancer immunity
Cancer Immunology Research, Vol. 7, Núm. 10, pp. 1664-1669
2018
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Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB)
OncoImmunology, Vol. 7, Núm. 1
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Epistatic oncogenic interactions determine cancer susceptibility to immunotherapy
Cancer Discovery, Vol. 8, Núm. 7, pp. 794-796
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Intratumoral immunotherapy with XCL1 and sFlt3L encoded in recombinant semliki forest virus–derived vectors fosters dendritic cell–mediated t-cell cross-priming
Cancer Research, Vol. 78, Núm. 23, pp. 6643-6654