Terapia Celular Adoptiva
Clínica Universitaria de Navarra
Pamplona, EspañaPublicaciones en colaboración con investigadores/as de Clínica Universitaria de Navarra (24)
2024
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Systemic messenger RNA replacement therapy is effective in a novel clinically relevant model of acute intermittent porphyria developed in non-human primates
Gut
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Tethered IL15-IL15Rα augments antitumor activity of CD19 CAR-T cells but displays long-term toxicity in an immunocompetent lymphoma mouse model
Journal for immunotherapy of cancer, Vol. 12, Núm. 7
2023
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Serum levels of S-100 protein are directly proportional to the size, number, thickness and degree of cellularity of congenital melanocytic nevi
Journal of the American Academy of Dermatology, Vol. 89, Núm. 5, pp. 1074-1077
2022
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Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma
New England Journal of Medicine, Vol. 386, Núm. 26, pp. 2471-2481
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Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 8
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Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
Cancer Discovery, Vol. 12, Núm. 5, pp. 1356-1377
2015
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Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression
Gene Therapy, Vol. 22, Núm. 11, pp. 856-865
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Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12
Cancer Research, Vol. 75, Núm. 3, pp. 497-507
2012
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CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy
Journal of Immunology, Vol. 189, Núm. 7, pp. 3299-3310
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Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer
Human Gene Therapy, Vol. 23, Núm. 12, pp. 1258-1268
2011
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Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy
International Journal of Cancer, Vol. 128, Núm. 1, pp. 105-118
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Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice
Gut, Vol. 60, Núm. 3, pp. 341-349
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
2010
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Delivery of immunostimulatory monoclonal antibodies by encapsulated hybridoma cells
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 11, pp. 1621-1631
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Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells
European Journal of Immunology, Vol. 40, Núm. 12, pp. 3389-3402
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Proliferating NK cells in response to IL-15 do not upregulate surface B220 in vivo
Gene Therapy
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2009
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In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
European Journal of Immunology, Vol. 39, Núm. 9, pp. 2424-2436
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Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes
British Journal of Cancer, Vol. 100, Núm. 7, pp. 1111-1119
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PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector
Gene Therapy, Vol. 16, Núm. 1, pp. 136-141