Terapias Avanzadas para Tumores Sólidos Pediátricos
University of Texas MD Anderson Cancer Center
Houston, Estados UnidosPublicaciones en colaboración con investigadores/as de University of Texas MD Anderson Cancer Center (62)
2024
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Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice
Molecular Therapy, Vol. 32, Núm. 3, pp. 722-733
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Genetically inferred birthweight, height, and puberty timing and risk of osteosarcoma
Cancer Epidemiology, Vol. 92
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International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma
The Lancet Oncology, Vol. 25, Núm. 5, pp. e205-e216
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Oncolytic adenoviruses and immunopeptidomics: a convenient marriage
Molecular Oncology
2023
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Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
Nature Medicine, Vol. 29, Núm. 6, pp. 1370-1378
2022
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Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas
JCI Insight, Vol. 7, Núm. 7
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Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory
Molecular Cancer Therapeutics, Vol. 21, Núm. 3, pp. 471-480
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Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma
New England Journal of Medicine, Vol. 386, Núm. 26, pp. 2471-2481
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Prospective validation of a new imaging scorecard to assess leptomeningeal metastasis: A joint EORTC BTG and RANO effort
Neuro-oncology, Vol. 24, Núm. 10, pp. 1726-1735
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Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry
Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 7
2021
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CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 7
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Current strategies to circumvent the antiviral immunity to optimize cancer virotherapy
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 4
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Delta-24-RGD, an oncolytic adenovirus, increases survival and promotes proinflammatory immune landscape remodeling in models of AT/RT and CNS-PNET
Clinical Cancer Research, Vol. 27, Núm. 6, pp. 1807-1820
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Hitchhiking to brain tumours: stem cell delivery of oncolytic viruses
The Lancet Oncology
2020
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Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients with Osteosarcoma
JAMA Oncology, Vol. 6, Núm. 5, pp. 724-734
2019
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Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models
Acta neuropathologica communications, Vol. 7, Núm. 1, pp. 64
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GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory
Neuro-Oncology Advances, Vol. 1, Núm. 1
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Localized treatment with oncolytic adenovirus delta-24-RGDOX induces systemic immunity against disseminated subcutaneous and intracranial melanomas
Clinical Cancer Research, Vol. 25, Núm. 22, pp. 6801-6814
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The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models
Nature Communications, Vol. 10, Núm. 1
2018
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DNX-2401, an oncolytic virus, for the treatment of newly diagnosed diffuse intrinsic pontine gliomas: A case report
Frontiers in Oncology, Vol. 8, Núm. MAR