Ignacio
Melero
Catedrático de Universidad
Publicaciones en las que colabora con Ignacio Melero (15)
2023
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Druggable Targets in Cytokine Release Syndromes
Clinical Cancer Research, Vol. 29, Núm. 21, pp. 4320-4322
2019
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Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses
Molecular Therapy, Vol. 27, Núm. 11, pp. 1892-1905
2018
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A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
Journal for ImmunoTherapy of Cancer, Vol. 6, Núm. 1
2015
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Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12
Cancer Research, Vol. 75, Núm. 3, pp. 497-507
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Virotherapy with a Semliki forest virus-based vector encoding IL12 synergizes with PD-1/PD-L1 blockade
Cancer Immunology Research, Vol. 3, Núm. 5, pp. 449-454
2012
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Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic semliki forest virus encoding IL-12
Molecular Therapy, Vol. 20, Núm. 9, pp. 1664-1675
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Virotherapy, gene transfer and immunostimulatory monoclonal antibodies
OncoImmunology, Vol. 1, Núm. 8, pp. 1344-1354
2011
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
2010
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Immunology and gene therapy: Shoulder to shoulder into the fray
Molecular Therapy
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
2005
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Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
Journal of Clinical Oncology, Vol. 23, Núm. 5, pp. 999-1010
2004
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Gene therapy of liver cancer: the present and the future
STATE OF THE ART HEPATOLOGY: MOLECULAR AND CELL BIOLOGY
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Phase I trial of intratumoral injection of an adenovirus encoding interleukin-12 for advanced digestive tumors
Journal of Clinical Oncology, Vol. 22, Núm. 8, pp. 1389-1397
2002
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Cytokine gene transfer into dendritic cells for cancer treatment.
Current gene therapy, Vol. 2, Núm. 1, pp. 79-89