Ignacio
Melero
Catedrático de Universidad
Publicaciones en las que colabora con Ignacio Melero (8)
2015
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Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression
Gene Therapy, Vol. 22, Núm. 11, pp. 856-865
2014
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Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus
PLoS ONE, Vol. 9, Núm. 1
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Liver Gene Therapy Approaches for Acute Intermittent Porphyria: Metabolic Correction and Immunological Hurdles
HANDBOOK OF PORPHYRIN SCIENCE WITH APPLICATIONS TO CHEMISTRY, PHYSICS, MATERIALS SCIENCE, ENGINEERING, BIOLOGY AND MEDICINE, VOL 29: PORPHYRIAS AND SIDEROBLASTIC ANEMIAS (WORLD SCIENTIFIC PUBL CO PTE LTD), pp. 415-450
2012
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Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
Journal of translational medicine, Vol. 10, pp. 122
2010
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Immunology and gene therapy: Shoulder to shoulder into the fray
Molecular Therapy
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
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Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria
Journal of Hepatology, Vol. 52, Núm. 3, pp. 417-424
2009
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PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector
Gene Therapy, Vol. 16, Núm. 1, pp. 136-141