Carlos
Alfaro Alegría
Investigador fins a 2017
José Luis
Pérez Gracia
Consultor Médico
Publicacions en què col·labora amb José Luis Pérez Gracia (30)
2020
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
Immunity, Vol. 52, Núm. 5, pp. 856-871.e8
2018
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A randomized phase II clinical trial of dendritic cell vaccination following complete resection of colon cancer liver metastasis 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis
Journal for ImmunoTherapy of Cancer, Vol. 6, Núm. 1
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Combined immunotherapy encompassing intratumoral poly-ICLC, dendritic-cell vaccination and radiotherapy in advanced cancer patients
Annals of Oncology, Vol. 29, Núm. 5, pp. 1312-1319
2017
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Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients
Annals of Oncology, Vol. 28, Núm. 8, pp. 1988-1995
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Interleukin-8 in cancer pathogenesis, treatment and follow-up
Cancer Treatment Reviews, Vol. 60, pp. 24-31
2016
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Tumor-Produced Interleukin-8 Attracts human myeloid-derived suppressor cells and elicits extrusion of Neutrophil Extracellular Traps (NETs)
Clinical Cancer Research, Vol. 22, Núm. 15, pp. 3924-3936
2015
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Functional expression of CD137 (4-1BB) on T helper follicular cells
OncoImmunology, Vol. 4, Núm. 12
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Nivolumab and urelumab enhance antitumor activity of human T lymphocytes engrafted in Rag2-/-IL2Rγnull immunodeficient mice
Cancer Research, Vol. 75, Núm. 17, pp. 3466-3478
2014
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Serum interleukin-8 reflects tumor burden and treatment response across malignancies of multiple tissue origins
Clinical Cancer Research, Vol. 20, Núm. 22, pp. 5697-5707
2013
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A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
Journal of Hepatology, Vol. 59, Núm. 1, pp. 81-88
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Células dendríticas especializadas en presentación de antígenos exógenos a linfocitos T citotóxicos
Anales del sistema sanitario de Navarra, Vol. 36, Núm. 3, pp. 519-537
2012
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Cardiotrophin-1 determines liver engraftment of syngenic colon carcinoma cells through an immune system-mediated mechanism
OncoImmunology, Vol. 1, Núm. 9, pp. 1527-1536
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The HIF-1α hypoxia response in tumor-infi ltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy
Cancer Discovery, Vol. 2, Núm. 7, pp. 608-623
2011
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Carcinoma-derived Interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation
PLoS ONE, Vol. 6, Núm. 3
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Dendritic cells take up and present antigens from viable and apoptotic polymorphonuclear leukocytes
PLoS ONE, Vol. 6, Núm. 12
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Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients
Journal of Immunology, Vol. 187, Núm. 11, pp. 6130-6142
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Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo
International Journal of Cancer, Vol. 129, Núm. 2, pp. 374-386
2010
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2009
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Clinical development of combination strategies in immunotherapy: Are we ready for more than one investigational product in an early clinical trial?
Immunotherapy, Vol. 1, Núm. 5, pp. 845-853
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In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb
European Journal of Immunology, Vol. 39, Núm. 9, pp. 2424-2436