Jesús María
Prieto Valtueña
Investigador hasta 2014
Ignacio
Melero
Catedrático de Universidad
Publicaciones en las que colabora con Ignacio Melero (42)
2019
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Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses
Molecular Therapy, Vol. 27, Núm. 11, pp. 1892-1905
2013
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A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
Journal of Hepatology, Vol. 59, Núm. 1, pp. 81-88
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Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein
Cancer Research, Vol. 73, Núm. 1, pp. 139-149
2012
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CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy
Journal of Immunology, Vol. 189, Núm. 7, pp. 3299-3310
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Liver Gene Transfer of Interkeukin-15 Constructs That Become Part of Circulating High Density Lipoproteins for Immunotherapy
PLoS ONE, Vol. 7, Núm. 12
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Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
Journal of translational medicine, Vol. 10, pp. 122
2010
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Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells
European Journal of Immunology, Vol. 40, Núm. 12, pp. 3389-3402
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Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primates
Molecular Therapy, Vol. 18, Núm. 4, pp. 754-765
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Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria
Journal of Hepatology, Vol. 52, Núm. 3, pp. 417-424
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Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ
Cancer Immunology, Immunotherapy, Vol. 59, Núm. 8, pp. 1223-1233
2007
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The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFNγ
International Journal of Cancer, Vol. 121, Núm. 6, pp. 1282-1295
2006
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El potencial de la inmunomodulación con anticuerpos monoclonales anti-CD137 (4-1BB) para terapia de enfermedades malignas e infecciones viráles crónicas
Anales del sistema sanitario de Navarra, Vol. 29, Núm. 1, pp. 77-96
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Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma
Cancer Research, Vol. 66, Núm. 4, pp. 2442-2450
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Recombinant Adenoviral Vectors Turn on the Type I Interferon System without Inhibition of Transgene Expression and Viral Replication
Molecular Therapy, Vol. 14, Núm. 1, pp. 129-138
2005
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Dendritic cells delivered inside human carcinomas are sequestered by interleukin-8
International Journal of Cancer, Vol. 116, Núm. 2, pp. 275-281
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Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus
Vaccine, Vol. 23, Núm. 27, pp. 3493-3499
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Gene therapy of cancer based on interleukin 12
Current Gene Therapy, Vol. 5, Núm. 6, pp. 573-581
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Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas
Journal of Clinical Oncology, Vol. 23, Núm. 5, pp. 999-1010
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Intratumoral injection of dendritic cells transduced by an SV40-based vector expressing interleukin-15 induces curative immunity mediated by CD8+ T lymphocytes and NK cells
Molecular Therapy, Vol. 12, Núm. 5, pp. 950-959
2004
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Biologic therapy of liver tumors
Surgical Clinics of North America, Vol. 84, Núm. 2, pp. 673-696