Publications en collaboration avec des chercheurs de Centro Nacional de Investigaciones Oncológicas (22)

2018

  1. Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

    Scientific Reports, Vol. 8, Núm. 1

2017

  1. Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

    Journal of Computer-Aided Molecular Design, Vol. 31, Núm. 12, pp. 1063-1072

2016

  1. Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

    ACS Chemical Biology, Vol. 11, Núm. 5, pp. 1401-1407

  2. Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

    Acta Crystallographica Section:F Structural Biology Communications, Vol. 72, pp. 473-479

2015

  1. Crystal structure of the homing endonuclease I-CvuI provides a new template for genome modification

    Journal of Biological Chemistry, Vol. 290, Núm. 48, pp. 28727-28736

  2. Engineering a nickase on the homing endonuclease I-DmoI Scaffold

    Journal of Biological Chemistry, Vol. 290, Núm. 30, pp. 18534-18544

  3. Visualizing phosphodiester-bond hydrolysis by an endonuclease

    Nature Structural and Molecular Biology, Vol. 22, Núm. 1, pp. 65-72

2013

  1. Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism

    Acta Crystallographica Section D: Biological Crystallography, Vol. 69, Núm. 9, pp. 1707-1716

2012

  1. Molecular scissors for in situ cellular repair

    Critical Reviews in Biochemistry and Molecular Biology, Vol. 47, Núm. 3, pp. 207-221

  2. Non-specific protein-DNA interactions control I-CreI target binding and cleavage

    Nucleic Acids Research, Vol. 40, Núm. 14, pp. 6936-6945

2011

  1. Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

    Nucleic Acids Research, Vol. 39, Núm. 2, pp. 729-743

  2. Reduced stability and increased dynamics in the human Proliferating Cell Nuclear Antigen (PCNA) relative to the yeast homolog

    PLoS ONE, Vol. 6, Núm. 2

2010

  1. Homing endonucleases: From basics to therapeutic applications

    Cellular and Molecular Life Sciences, Vol. 67, Núm. 5, pp. 727-748

  2. Solution structure of human growth arrest and DNA damage 45α(Gadd45α) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

    Journal of Biological Chemistry, Vol. 285, Núm. 29, pp. 22196-22201

2009

  1. Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

    Nucleic Acids Research, Vol. 37, Núm. 16, pp. 5405-5419

2008

  1. Crystal structure of I-DmoI in complex with its target DNA provides new insights into meganuclease engineering

    Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Núm. 44, pp. 16888-16893

  2. Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

    Nature, Vol. 456, Núm. 7218, pp. 107-111

  3. NMR assignment and secondary structure of human growth arrest and DNA damage α protein (Gadd45α)

    Biomolecular NMR Assignments, Vol. 2, Núm. 2, pp. 139-142

2007

  1. Backbone assignment of human proliferating cell nuclear antigen

    Biomolecular NMR Assignments, Vol. 1, Núm. 2, pp. 245-247

  2. Crystallization and preliminary X-ray diffraction analysis on the homing endonuclease I-Dmo-I in complex with its target DNA

    Acta Crystallographica Section F: Structural Biology and Crystallization Communications, Vol. 63, Núm. 12, pp. 1017-1020