Publicaciones en colaboración con investigadores/as de Centro Nacional de Investigaciones Oncológicas (27)

2019

  1. Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors

    European Journal of Medicinal Chemistry, Vol. 168, pp. 87-109

2012

  1. Conformational selection versus induced fit in kinases: The case of PI3K-Iγ

    Angewandte Chemie - International Edition, Vol. 51, Núm. 3, pp. 642-646

  2. Fragment-Hopping-Based Discovery of a Novel Chemical Series of Proto-Oncogene PIM-1 Kinase Inhibitors

    PLoS ONE, Vol. 7, Núm. 10

  3. Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 4, pp. 1591-1597

  4. Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor

    Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 10, pp. 3460-3466

  5. Imidazo[1,2-a]pyrazines as novel PI3K inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 5, pp. 1874-1878

  6. Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR

    Bioorganic and Medicinal Chemistry Letters, Vol. 22, Núm. 16, pp. 5208-5214