Iván
Peñuelas Sánchez
Investigador Consultor
Centro de Investigación Médica Aplicada
Pamplona, EspañaCentro de Investigación Médica Aplicada-ko ikertzaileekin lankidetzan egindako argitalpenak (46)
2023
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A novel [89Zr]-anti-PD-1-PET-CT to assess response to PD-1/PD-L1 blockade in lung cancer
Frontiers in Immunology, Vol. 14
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Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates
Brain : a journal of neurology, Vol. 146, Núm. 12, pp. 5000-5014
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Nutritional Interventions with Bacillus coagulans Improved Glucose Metabolism and Hyperinsulinemia in Mice with Acute Intermittent Porphyria
International Journal of Molecular Sciences, Vol. 24, Núm. 15
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TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
Cancer Cell, Vol. 41, Núm. 11, pp. 1911-1926.e8
2022
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A new animal model of atrophy–hypertrophy complex and liver damage following Yttrium-90 lobar selective internal radiation therapy in rabbits
Scientific Reports, Vol. 12, Núm. 1
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High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease
Molecular Therapy - Methods and Clinical Development, Vol. 26, pp. 98-106
2021
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Glucocerebrosidase gene therapy induces alpha-synuclein clearance and neuroprotection of midbrain dopaminergic neurons in mice and macaques
International Journal of Molecular Sciences, Vol. 22, Núm. 9
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mRNA-based therapy in a rabbit model of variegate porphyria offers new insights into the pathogenesis of acute attacks
Molecular Therapy - Nucleic Acids, Vol. 25, pp. 207-219
2020
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In vivo efficacy of bevacizumab-loaded albumin nanoparticles in the treatment of colorectal cancer
Drug Delivery and Translational Research, Vol. 10, Núm. 3, pp. 635-645
2019
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Preclinical safety of topically administered nanostructure lipid carriers (NLC) for wound healing application: biodistribution and toxicity studies
International Journal of Pharmaceutics, Vol. 569
2018
2017
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Lessons from 11C-dihydrotetrabenazine imaging in a xenograft mouse model of rat insulinoma: Is PET imaging of pancreatic beta cell mass feasible?
Quarterly Journal of Nuclear Medicine and Molecular Imaging, Vol. 61, Núm. 4, pp. 447-455
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Non-invasive in vivo imaging of cardiac stem/progenitor cell biodistribution and retention after intracoronary and intramyocardial delivery in a swine model of chronic ischemia reperfusion injury
Journal of Translational Medicine, Vol. 15, Núm. 1
2016
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Glucose metabolism during fasting is altered in experimental porphobilinogen deaminase deficiency
Human Molecular Genetics, Vol. 25, Núm. 7, pp. 1318-1327
2015
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Infiltration of plasma rich in growth factors enhances in vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia
Journal of Controlled Release, Vol. 202, pp. 31-39
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Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of Parkinson's disease: A longitudinal in-vivo study
Neurobiology of Disease, Vol. 77, pp. 165-172
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Radiation dosimetry and biodistribution in non-human primates of the sodium/iodide PET ligand [18F]-tetrafluoroborate
EJNMMI Research, Vol. 5, Núm. 1, pp. 1-9
2014
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In vivo monitoring of staphylococcus aureus biofilm infections and antimicrobial therapy by [18F] Fluoro-Deoxyglucose-MicroPET in a Mouse Model
Antimicrobial Agents and Chemotherapy, Vol. 58, Núm. 11, pp. 6660-6667
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Levodopa induces long-lasting modification in the functional activity of the nigrostriatal pathway
Neurobiology of Disease, Vol. 62, pp. 250-259
2013
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Radiolabeling and biodistribution studies of polymeric nanoparticles as adjuvants for ocular vaccination against brucellosis
Revista Espanola de Medicina Nuclear e Imagen Molecular, Vol. 32, Núm. 2, pp. 92-97