Felipe
Prosper Cardoso
Consultor Médico
Edurne
San José Enériz
Investigadora Asociada
Publicaciones en las que colabora con Edurne San José Enériz (46)
2024
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An automated network-based tool to search for metabolic vulnerabilities in cancer
Nature Communications , Vol. 15, Núm. 1
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Epigenetic-based differentiation therapy for Acute Myeloid Leukemia
Nature Communications, Vol. 15, Núm. 1
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Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer
Cell Death Discovery, Vol. 10, Núm. 1
2022
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Explainable artificial intelligence for precision medicine in acute myeloid leukemia
Frontiers in Immunology, Vol. 13
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Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma
Frontiers in Immunology, Vol. 13
2021
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Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with in Vivo Efficacy in Multiple Myeloma
Journal of Medicinal Chemistry, Vol. 64, Núm. 6, pp. 3392-3426
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Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease
Nature Communications, Vol. 12, Núm. 1
2020
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Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma
Blood, Vol. 136, Núm. 2, pp. 199-209
2019
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Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma
Hepatology, Vol. 69, Núm. 2, pp. 587-603
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HDAC inhibitors in acute myeloid leukemia
Cancers, Vol. 11, Núm. 11
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Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression
Nature Medicine
2018
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COBRA methods and metabolic drug targets in cancer
Molecular and Cellular Oncology, Vol. 5, Núm. 1
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Deregulation of linc-PINT in acute lymphoblastic leukemia is implicated in abnormal proliferation of leukemic cells
Oncotarget, Vol. 9, Núm. 16, pp. 12842-12852
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Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6546-6573
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
2017
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An in-silico approach to predict and exploit synthetic lethality in cancer metabolism
Nature Communications, Vol. 8, Núm. 1
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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies
Nature Communications, Vol. 8
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Dual epigenetic modifiers for cancer therapy
Molecular and Cellular Oncology, Vol. 4, Núm. 4
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In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer
Scientific Reports, Vol. 7, Núm. 1
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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome
PLoS ONE, Vol. 12, Núm. 12