Publicaciones (44) Publicaciones de Juan Roberto Rodríguez Madoz

2023

  1. FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma

    Molecular Therapy, Vol. 31, Núm. 1, pp. 48-65

  2. Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia

    Frontiers in Immunology, Vol. 14

  3. Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi

    Molecular Therapy Nucleic Acids, Vol. 34

  4. Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures

    Stem Cell Reports, Vol. 18, Núm. 1, pp. 64-80

2022

  1. CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

    Science Advances, Vol. 8, Núm. 39

  2. Generation of NKX2.5GFP Reporter Human iPSCs and Differentiation Into Functional Cardiac Fibroblasts

    Frontiers in Cell and Developmental Biology, Vol. 9

  3. In vivo CRISPR-Cas9 inhibition of hepatic LDH as treatment of primary hyperoxaluria

    Molecular Therapy - Methods and Clinical Development, Vol. 25, pp. 137-146

  4. One-Step In Vitro Generation of ETV2-Null Pig Embryos

    Animals, Vol. 12, Núm. 14

  5. Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy

    OncoImmunology, Vol. 11, Núm. 1

  6. SimiC enables the inference of complex gene regulatory dynamics across cell phenotypes

    Communications Biology, Vol. 5, Núm. 1

  7. Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

    Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 8

  8. Time 2EVOLVE: predicting efficacy of engineered T-cells - how far is the bench from the bedside?

    Journal for immunotherapy of cancer, Vol. 10, Núm. 5

2021

  1. Online monitoring of hiPSC expansion and hepatic differentiation in 3D culture by dielectric spectroscopy

    Biotechnology and Bioengineering, Vol. 118, Núm. 9, pp. 3610-3617

  2. Small molecule-based enzyme inhibitors in the treatment of primary hyperoxalurias

    Journal of Personalized Medicine, Vol. 11, Núm. 2, pp. 1-31

2020

  1. Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma

    Genome Research, Vol. 30, Núm. 9, pp. 1217-1227

  2. Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors

    Journal of Tissue Engineering and Regenerative Medicine, Vol. 14, Núm. 1, pp. 123-134

2019

  1. Generation of an induced pluripotent stem cell line (CIMAi001-A) from a compound heterozygous Primary Hyperoxaluria Type I (PH1) patient carrying p.G170R and p.R122* mutations in the AGXT gene.

    Stem Cell Research, Vol. 41

  2. Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization

    Molecular Therapy - Methods and Clinical Development, Vol. 15, pp. 403-417

2018

  1. CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I

    Nature Communications, Vol. 9, Núm. 1

2017

  1. Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

    Nature Communications, Vol. 8