Publicaciones (81) Publicaciones de Silvia Pérez Silanes

2024

  1. Novel Pitolisant-Derived Sulfonyl Compounds for Alzheimer Disease

    International Journal of Molecular Sciences, Vol. 25, Núm. 2

  2. Promising aryl selenoate derivatives as antileishmanial agents and their effects on gene expression

    Antimicrobial Agents and Chemotherapy, Vol. 68, Núm. 4

2023

  1. Neglected Zoonotic Diseases: Advances in the Development of Cell-Penetrating and Antimicrobial Peptides against Leishmaniosis and Chagas Disease

    Pathogens, Vol. 12, Núm. 7

2022

  1. Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease

    Bioorganic and Medicinal Chemistry, Vol. 58

  2. Potential of sulfur-selenium isosteric replacement as a strategy for the development of new anti-chagasic drugs

    Acta Tropica, Vol. 233

2021

  1. Design and synthesis of Mannich base-type derivatives containing imidazole and benzimidazole as lead compounds for drug discovery in Chagas Disease

    European Journal of Medicinal Chemistry, Vol. 223

2020

  1. Selenium as an interesting option for the treatment of Chagas disease: A review

    European Journal of Medicinal Chemistry, Vol. 206

  2. The role of imidazole and benzimidazole heterocycles in Chagas disease: A review

    European Journal of Medicinal Chemistry, Vol. 206

2019

  1. A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives

    European Journal of Medicinal Chemistry, Vol. 163, pp. 569-582

  2. Antichagasic profile of a Series of Mannich Base-Type Derivatives: Design, Synthesis, in vitro Evaluation, and Computational Studies Involving Iron Superoxide Dismutase

    ChemistrySelect, Vol. 4, Núm. 27, pp. 8112-8121

  3. Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation

    Bioorganic and Medicinal Chemistry, Vol. 27, Núm. 17, pp. 3902-3917

2018

  1. Organometallic compounds in the discovery of new agents against kinetoplastid-caused diseases

    European Journal of Medicinal Chemistry, Vol. 155, pp. 459-482

  2. Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi

    Journal of Medicinal Chemistry, Vol. 61, Núm. 13, pp. 5643-5663

2017

  1. A Comparative Study of Conventional and Microwave-Assisted Synthesis of Quinoxaline 1,4-di-N-oxide N-acylhydrazones Derivatives Designed as Antitubercular Drug Candidates

    Journal of Heterocyclic Chemistry, Vol. 54, Núm. 4, pp. 2380-2388

  2. Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity

    Journal of Medicinal Chemistry, Vol. 60, Núm. 20, pp. 8647-8660

  3. Development, validation and application of a GC–MS method for the simultaneous detection and quantification of neutral lipid species in Trypanosoma cruzi

    Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 1061-1062, pp. 225-232

  4. In vitro antileishmanial activity and iron superoxide dismutase inhibition of arylamine Mannich base derivatives

    Parasitology, Vol. 114, Núm. 13, pp. 1783-1790

  5. Library of seleno-compounds as novel agents against Leishmania species

    Antimicrobial Agents and Chemotherapy, Vol. 61, Núm. 6

  6. Planejamento, síntese e atividade anti-Mycobacterium tuberculosis de derivados N-óxidos

    Revista de Ciencias Farmaceuticas Basica e Aplicada

  7. Trypanothione reductase and superoxide dismutase as current drug targets for Trypanosoma cruzi: An overview of compounds with activity against chagas disease

    Current Medicinal Chemistry, Vol. 24, Núm. 11, pp. 1066-1138