Tomás
Aragón Amonarriz
Profesional Investigador
Centro de Investigación Médica Aplicada
Pamplona, EspañaPublicacions en col·laboració amb investigadors/es de Centro de Investigación Médica Aplicada (20)
2024
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Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model
British Journal of Pharmacology, Vol. 181, Núm. 3, pp. 495-508
2023
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Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis (Nature Communications, (2019), 10, 1, (3126), 10.1038/s41467-019-11004-3)
Nature Communications
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Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models
Neurobiology of Disease, Vol. 183
2022
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Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α
eLife, Vol. 11
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The Role and Therapeutic Potential of the Integrated Stress Response in Amyotrophic Lateral Sclerosis
International Journal of Molecular Sciences, Vol. 23, Núm. 14
2021
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Linking the Expression of Therapeutic Genes to Unfolded Protein Response: A New Option for Anti-Hepatitis B Virus Gene Therapy
Human Gene Therapy, Vol. 32, Núm. 7-8, pp. 341-348
2020
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Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis
Cell Death and Disease, Vol. 11, Núm. 5
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Maturation of NAA20 Aminoterminal End Is Essential to Assemble NatB N-Terminal Acetyltransferase Complex
Journal of Molecular Biology, Vol. 432, Núm. 22, pp. 5889-5901
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N-terminal acetylation mutants affect alpha-synuclein stability, protein levels and neuronal toxicity
Neurobiology of Disease, Vol. 137
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The importance of naturally attenuated SARS-CoV-2in the fight against COVID-19
Environmental Microbiology, Vol. 22, Núm. 6, pp. 1997-2000
2019
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Nature Communications, Vol. 10, Núm. 1
2018
2017
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Iron affects Ire1 clustering propensity and the amplitude of endoplasmic reticulum stress signaling
Journal of Cell Science, Vol. 130, Núm. 19, pp. 3222-3233
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The Ire1 Twist that Links Proteostatic with Lipostatic Control of the Endoplasmic Reticulum
Trends in Cell Biology
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X-box Binding Protein 1 Regulates Unfolded Protein, Acute-Phase, and DNA Damage Responses During Regeneration of Mouse Liver
Gastroenterology, Vol. 152, Núm. 5, pp. 1203-1216.e15
2016
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Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51
Neuro-Oncology, Vol. 18, Núm. 8, pp. 1109-1119
2014
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Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation
Journal of Hepatology, Vol. 60, Núm. 5, pp. 1017-1025
2013
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Helper-dependent adenoviral liver gene therapy protects against induced attacks and corrects protein folding stress in acute intermittent porphyria mice
Human Molecular Genetics, Vol. 22, Núm. 14, pp. 2929-2940
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Phenyl Acyl Acids Attenuate the Unfolded Protein Response in Tunicamycin-Treated Neuroblastoma Cells
PLoS ONE, Vol. 8, Núm. 8
2010
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BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response
PLoS Biology, Vol. 8, Núm. 7