Rafael
Aldabe Arregui
Profesional Investigador
Publicacións (55) Publicacións de Rafael Aldabe Arregui
2024
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Deciphering the Role of Post-Translational Modifications and Cellular Location of Hepatitis Delta Virus (HDV) Antigens in HDV-Mediated Liver Damage in Mice
Viruses, Vol. 16, Núm. 3
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Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice
PLoS ONE, Vol. 19, Núm. 5
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Multiscale and multimodal evaluation of autosomal dominant polycystic kidney disease development
Communications Biology, Vol. 7, Núm. 1
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NatB Protects Procaspase-8 from UBR4-Mediated Degradation and Is Required for Full Induction of the Extrinsic Apoptosis Pathway
Molecular and Cellular Biology, Vol. 44, Núm. 9, pp. 358-371
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Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice
PLoS Pathogens, Vol. 20, Núm. 5
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The infectivity of AAV9 is influenced by the specific location and extent of chemically modified capsid residues
Journal of Biological Engineering, Vol. 18, Núm. 1
2023
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NatB Catalytic Subunit Depletion Disrupts DNA Replication Initiation Leading to Senescence in MEFs
International Journal of Molecular Sciences, Vol. 24, Núm. 10
2022
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Gene Therapy in Combination with Nitrogen Scavenger Pretreatment Corrects Biochemical and Behavioral Abnormalities of Infant Citrullinemia Type 1 Mice
International Journal of Molecular Sciences, Vol. 23, Núm. 23
2021
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Aav-hdv: An attractive platform for the in vivo study of hdv biology and the mechanism of disease pathogenesis
Viruses, Vol. 13, Núm. 5
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Consequences of Mammalian Target of Rapamycin Inhibition on Adeno-Associated Virus Hepatic Transduction Efficacy
Human Gene Therapy, Vol. 32, Núm. 19-20, pp. 1242-1250
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Novel vectors and approaches for gene therapy in liver diseases
JHEP Reports, Vol. 3, Núm. 4
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Oligonucleotide-based therapies for renal diseases
Biomedicines, Vol. 9, Núm. 3
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Use of an adeno-associated virus serotype Anc80 to provide durable cure of phenylketonuria in a mouse model
Journal of Inherited Metabolic Disease, Vol. 44, Núm. 6, pp. 1369-1381
2020
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Maturation of NAA20 Aminoterminal End Is Essential to Assemble NatB N-Terminal Acetyltransferase Complex
Journal of Molecular Biology, Vol. 432, Núm. 22, pp. 5889-5901
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N-terminal acetylation mutants affect alpha-synuclein stability, protein levels and neuronal toxicity
Neurobiology of Disease, Vol. 137
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TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection
JHEP Reports, Vol. 2, Núm. 3
2018
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Erratum to “A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction” [J Hepatol 67 (2017) 669–679] (S0168827817320469) (10.1016/j.jhep.2017.05.010))
Journal of Hepatology
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N-terminal acetylation modulates Bax targeting to mitochondria
International Journal of Biochemistry and Cell Biology, Vol. 95, pp. 35-42
2017
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A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction
Journal of Hepatology, Vol. 67, Núm. 4, pp. 669-679
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NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma
Oncotarget, Vol. 8, Núm. 25, pp. 40967-40981