José Ignacio
Fernández de Trocóniz Fernández
Catedrático de Universidad
Victor
Mangas Sanjuan
Victor Mangas Sanjuan-rekin lankidetzan egindako argitalpenak (11)
2023
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Mechanistic characterization of oscillatory patterns in unperturbed tumor growth dynamics: The interplay between cancer cells and components of tumor microenvironment
PLoS Computational Biology, Vol. 19, Núm. 10
2021
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Semi-mechanistic model for the antitumor response of a combination cocktail of immuno-modulators in non-inflamed (Cold) tumors
Cancers, Vol. 13, Núm. 20
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The role of mathematical models in immuno-oncology: Challenges and future perspectives
Pharmaceutics, Vol. 13, Núm. 7
2018
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Computer simulations for bioequivalence trials: Selection of analyte in BCS class II and IV drugs with first-pass metabolism, two metabolic pathways and intestinal efflux transporter
European Journal of Pharmaceutical Sciences, Vol. 117, pp. 193-203
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Semi-mechanistic Pharmacokinetic/Pharmacodynamic model of three pegylated rHuEPO and ior®EPOCIM in New Zealand rabbits
European Journal of Pharmaceutical Sciences, Vol. 120, pp. 123-132
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Systematic modeling and design evaluation of unperturbed tumor dynamics in xenografts
Journal of Pharmacology and Experimental Therapeutics, Vol. 366, Núm. 1, pp. 96-104
2016
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Population pharmacokinetic model of lithium and drug compliance assessment
European Neuropsychopharmacology, Vol. 26, Núm. 12, pp. 1868-1876
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Population pharmacokinetic/pharmacodynamic modelling of the effects of axomadol and its O-demethyl metabolite on pupil diameter and nociception in healthy subjects
British Journal of Clinical Pharmacology, pp. 92-107
2015
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Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid
European Journal of Pharmaceutical Sciences, Vol. 74, pp. 86-94
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Semimechanistic cell-cycle type-based pharmacokinetic/pharmacodynamic model of chemotherapy-induced neutropenic effects of diflomotecan under different dosing schedules
Journal of Pharmacology and Experimental Therapeutics, Vol. 354, Núm. 1, pp. 55-64
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Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients
European Journal of Pharmaceutical Sciences, Vol. 73, pp. 57-63