Publicaciones en colaboración con investigadores/as de Centro de Investigación Médica Aplicada (18)

2022

  1. Mechanistic modelling of enzyme-restoration effects of new recombinant liver-targeted proteins in acute intermittent porphyria

    British Journal of Pharmacology, Vol. 179, Núm. 14, pp. 3815-3830

  2. Prognostic Value of Serum Paraprotein Response Kinetics in Patients With Newly Diagnosed Multiple Myeloma

    Clinical Lymphoma, Myeloma and Leukemia, Vol. 22, Núm. 9, pp. e844-e852

2021

  1. Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model

    Journal of Nanobiotechnology, Vol. 19, Núm. 1

  2. Modulation of intratumoural myeloid cells, the hallmark of the anti-tumour efficacy induced by a triple combination: tumour-associated peptide, TLR-3 ligand and α-PD-1

    British Journal of Cancer, Vol. 124, Núm. 7, pp. 1275-1285

  3. Semi-mechanistic model for the antitumor response of a combination cocktail of immuno-modulators in non-inflamed (Cold) tumors

    Cancers, Vol. 13, Núm. 20

2020

  1. Disease pharmacokinetic–pharmacodynamic modelling in acute intermittent porphyria to support the development of mRNA-based therapies

    British Journal of Pharmacology, Vol. 177, Núm. 14, pp. 3168-3182

2019

  1. A new immune-nanoplatform for promoting adaptive antitumor immune response

    Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 17, pp. 13-25

2017

  1. Commentary on Pharmacometrics for Immunotherapy

    CPT: Pharmacometrics and Systems Pharmacology, Vol. 6, Núm. 1, pp. 8-10

  2. Effect of dexmedetomidine and propofol on basal ganglia activity in Parkinson disease a controlled clinical trial

    Anesthesiology, Vol. 126, Núm. 6, pp. 1033-1042

2013

  1. Mathematical model approach to describe tumour response in mice after vaccine administration and its applicability to immune-stimulatory cytokine-based strategies

    AAPS Journal, Vol. 15, Núm. 3, pp. 797-807

  2. Modeling tumor response after combined administration of different immune-stimulatory agentss

    Journal of Pharmacology and Experimental Therapeutics, Vol. 346, Núm. 3, pp. 432-442

  3. Target-mediated disposition model describing the dynamics of IL12 and IFNγ after administration of a mifepristone-inducible adenoviral vector for IL-12 expression in mice

    AAPS Journal, Vol. 15, Núm. 1, pp. 183-194

2012

  1. Kinetic and dynamic computational model-based characterization of new proteins in mice: Application to interferon alpha linked to apolipoprotein A-I

    PLoS ONE, Vol. 7, Núm. 7

2010

  1. A semi-physiological-based pharmacokinetic/pharmacodynamic model to describe the effects of topotecan on B-lymphocyte lineage cells

    Pharmaceutical Research, Vol. 27, Núm. 3, pp. 431-441

  2. Gene therapy: A pharmacokinetic/pharmacodynamic modelling overview

    Pharmaceutical Research, Vol. 27, Núm. 8, pp. 1487-1497

2009

  1. Semi-mechanistic pharmacodynamic modelling of gene expression and silencing processes

    European Journal of Pharmaceutical Sciences, Vol. 37, Núm. 3-4, pp. 418-426

2008

  1. Semi-mechanistic description of the in-vitro antiproliferative effect of different antitumour agents

    Journal of Pharmacy and Pharmacology, Vol. 60, Núm. 1, pp. 77-82

2006

  1. Intrahepatic injection of recombinant adeno-associated virus serotype 2 overcomes gender-related differences in liver transduction

    Human Gene Therapy, Vol. 17, Núm. 6, pp. 601-610