Publications en collaboration avec des chercheurs de Universidad del País Vasco/Euskal Herriko Unibertsitatea (19)

2015

  1. Population pharmacokinetic models for cefuroxime and metronidazole used in combination as prophylactic agents in colorectal surgery: Model-based evaluation of standard dosing regimens

    International Journal of Antimicrobial Agents, Vol. 45, Núm. 5, pp. 504-511

2014

  1. Population pharmacokinetics of piperacillin and tazobactam in critically ill patients undergoing continuous renal replacement therapy: Application to pharmacokinetic/pharmacodynamic analysis

    Journal of Antimicrobial Chemotherapy, Vol. 69, Núm. 1, pp. 180-189

2012

  1. Population pharmacokinetics of prophylactic cefoxitin in patients undergoing colorectal surgery

    European Journal of Clinical Pharmacology, Vol. 68, Núm. 5, pp. 735-745

2011

  1. Pharmacokinetic/pharmacodynamic evaluation of amoxicillin, amoxicillin/clavulanate and ceftriaxone in the treatment of paediatric acute otitis media in Spain

    Enfermedades Infecciosas y Microbiologia Clinica, Vol. 29, Núm. 3, pp. 167-173

2010

  1. A semi-physiological-based pharmacokinetic/pharmacodynamic model to describe the effects of topotecan on B-lymphocyte lineage cells

    Pharmaceutical Research, Vol. 27, Núm. 3, pp. 431-441

2008

  1. Population pharmacokinetics of meropenem in critically ill patients undergoing continuous renal replacement therapy

    Clinical Pharmacokinetics, Vol. 47, Núm. 3, pp. 173-180

2000

  1. Alpha1-acid glycoprotein (AAG) and serum protein binding of methadone in heroin addicts with abstinence syndrome

    International Journal of Clinical Pharmacology and Therapeutics, Vol. 38, Núm. 1, pp. 35-40

  2. Modeling of the in vivo antinociceptive interaction between an opioid agonist, (+)-O-desmethyltramadol, and a monoamine reuptake inhibitor, (-)-O-desmethyltramadol, in rats

    Journal of Pharmacology and Experimental Therapeutics, Vol. 295, Núm. 1, pp. 352-359

  3. Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effects of main active metabolites of tramadol, (+)-O-desmethyltramadol and (-)-O- desmethyltramadol, in rats

    Journal of Pharmacology and Experimental Therapeutics, Vol. 293, Núm. 2, pp. 646-653

  4. Pharmacokinetic-pharmacodynamic modelling of the antipyretic effect of two oral formulations of ibuprofen

    Clinical Pharmacokinetics, Vol. 38, Núm. 6, pp. 505-518

1999

  1. Altered plasma and brain disposition and pharmacodynamics of methadone in abstinent rats

    Journal of Pharmacology and Experimental Therapeutics, Vol. 288, Núm. 1, pp. 179-187

  2. Enantiomeric separation of tramadol and its active metabolite in human plasma by chiral high-performance liquid chromatography: Application to pharmacokinetic studies

    Chirality, Vol. 11, Núm. 4, pp. 272-279

  3. Simultaneous determination of tramadol and its major active metabolite O-demethyltramadol by high-performance liquid chromatography with electrochemical detection

    Journal of Chromatography B: Biomedical Sciences and Applications, Vol. 724, Núm. 1, pp. 83-89

1998

  1. Serum protein binding of lerisetron, a novel specific 5HT3 antagonist, in patients with cancer

    Cancer Chemotherapy and Pharmacology, Vol. 42, Núm. 5, pp. 418-422

1997

  1. Pharmacokinetic-pharmacodynamic modeling of mivacurium in rats

    Journal of Pharmaceutical Sciences, Vol. 86, Núm. 2, pp. 252-256

1996

  1. Pharmacokinetics and pharmacodynamics of penbutolol in healthy and cancer subjects: Role of altered protein binding

    Research Communications in Molecular Pathology and Pharmacology, Vol. 92, Núm. 1, pp. 53-72

  2. Population-based approach to the assessment of pharmacokinetic-pharmacodynamic data

    Methods and Findings in Experimental and Clinical Pharmacology

1995

  1. Resistance to atracurium in rats with experimental inflammation: role of protein binchng

    Acta Anaesthesiologica Scandinavica, Vol. 39, Núm. 8, pp. 1019-1023

  2. Tenoxicam pharmacokinetics in rats: A population model

    Journal of Pharmaceutical Sciences, Vol. 84, Núm. 12, pp. 1482-1487