José Ignacio
Fernández de Trocóniz Fernández
Catedrático de Universidad
Uppsala University
Upsala, SueciaPublicaciones en colaboración con investigadores/as de Uppsala University (10)
2015
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Optimizing oncology therapeutics through quantitative translational and clinical pharmacology: Challenges and opportunities
Clinical Pharmacology and Therapeutics, Vol. 97, Núm. 1, pp. 37-54
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Pharmacometrics Markup Language (PharmML): Opening new perspectives for model exchange in drug development
CPT: Pharmacometrics and Systems Pharmacology, Vol. 4, Núm. 6, pp. 316-319
2014
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A review of mixed-effects models of tumor growth and effects of anticancer drug treatment used in population analysis
CPT: Pharmacometrics and Systems Pharmacology, Vol. 3, Núm. 5
2011
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Predictive ability of a semi-mechanistic model for neutropenia in the development of novel anti-cancer agents: Two case studies
Investigational New Drugs, Vol. 29, Núm. 5, pp. 984-995
2010
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Incorporating physiological and biochemical mechanisms into pharmacokinetic-pharmacodynamic models: A conceptual framework
Basic and Clinical Pharmacology and Toxicology
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Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics
European Journal of Cancer, Vol. 46, Núm. 1, pp. 21-32
2009
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Modelling overdispersion and markovian features in count data
Journal of Pharmacokinetics and Pharmacodynamics, Vol. 36, Núm. 5, pp. 461-477
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Performance in population models for count data, part I: Maximum likelihood approximations
Journal of Pharmacokinetics and Pharmacodynamics, Vol. 36, Núm. 4, pp. 353-366
2004
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Modelling and simulation in the development and use of anti-cancer agents: An underused tool?
Journal of Pharmacokinetics and Pharmacodynamics
1998
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Population pharmacodynamic modeling of levodopa in patients with Parkinson's disease receiving entacapone
Clinical Pharmacology and Therapeutics, Vol. 64, Núm. 1, pp. 106-116