José Ángel
Martínez Climent
Investigador Senior
Felipe
Prosper Cardoso
Consultor Médico
Publicaciones en las que colabora con Felipe Prosper Cardoso (26)
2024
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Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma
Blood cancer discovery, Vol. 5, Núm. 3, pp. 146-152
2023
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
2022
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Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma
Science Advances, Vol. 8, Núm. 3
2021
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Endogenous retroelement activation by epigenetic therapy reverses the warburg effect and elicits mitochondrial-mediated cancer cell death
Cancer Discovery, Vol. 11, Núm. 5, pp. 1268-1285
2018
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Detailed Exploration around 4-Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6546-6573
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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy
Journal of Medicinal Chemistry, Vol. 61, Núm. 15, pp. 6518-6545
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Richter transformation driven by Epstein–Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia
Journal of Pathology, Vol. 245, Núm. 1, pp. 61-73
2017
2016
2012
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Epigenetic regulation of miRNA genes in acute leukemia
Leukemia, Vol. 26, Núm. 3, pp. 395-403
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Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice
Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Núm. 26, pp. 10534-10539
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High-throughput sequencing analysis of the chromosome 7q32 deletion reveals IRF5 as a potential tumour suppressor in splenic marginal-zone lymphoma
British Journal of Haematology, Vol. 158, Núm. 6, pp. 712-726
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Preclinical activity of LBH589 alone or in combination with chemotherapy in a xenogeneic mouse model of human acute lymphoblastic leukemia
Leukemia, Vol. 26, Núm. 7, pp. 1517-1526
2011
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A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma
Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Núm. 30, pp. 12461-12466
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LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome
Haematologica, Vol. 96, Núm. 7, pp. 980-986
2010
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Lymphoma stem cells: Enough evidence to support their existence?
Haematologica, Vol. 95, Núm. 2, pp. 293-302
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Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma
Blood, Vol. 116, Núm. 14, pp. 2531-2542
2009
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Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia
European Journal of Cancer, Vol. 45, Núm. 10, pp. 1877-1889
2007
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Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
Blood, Vol. 109, Núm. 1, pp. 271-280
2006
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Somatic stem cells and the origin of cancer
Clinical and Translational Oncology, Vol. 8, Núm. 9, pp. 647-663