Juan José
Lasarte Sagastibelza
Catedrático de Universidad
Teresa
Lozano Moreda
Profesional Investigadora
Publicacións nas que colabora con Teresa Lozano Moreda (38)
2024
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AI is a viable alternative to high throughput screening: a 318-target study
Scientific Reports, Vol. 14, Núm. 1
2023
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FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma
Molecular Therapy, Vol. 31, Núm. 1, pp. 48-65
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Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses
Cancer Letters, Vol. 561
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PTEN Loss Confers Resistance to Anti–PD-1 Therapy in Non–Small Cell Lung Cancer by Increasing Tumor Infiltration of Regulatory T Cells
Cancer Research, Vol. 83, Núm. 15, pp. 2513-2526
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Nature Medicine, Vol. 29, Núm. 3, pp. 632-645
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The transcriptional regulator Sin3A balances IL-17A and Foxp3 expression in primary CD4 T cells
EMBO Reports, Vol. 24, Núm. 5
2022
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CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome
Science Advances, Vol. 8, Núm. 39
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Impact of tumor microenvironment on adoptive T cell transfer activity
International Review of Cell and Molecular Biology (Elsevier Inc.), pp. 1-31
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Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer
Molecular Therapy - Nucleic Acids, Vol. 29, pp. 387-399
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Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy
OncoImmunology, Vol. 11, Núm. 1
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TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity
Cancer Letters, Vol. 528, pp. 45-58
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Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells
Journal for ImmunoTherapy of Cancer, Vol. 10, Núm. 8
2021
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Intratumoral STING Agonist Injection Combined with Irreversible Electroporation Delays Tumor Growth in a Model of Hepatocarcinoma
BioMed Research International, Vol. 2021
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SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation
Journal for ImmunoTherapy of Cancer, Vol. 9, Núm. 3
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Searching for peptide inhibitors of t regulatory cell activity by targeting specific domains of foxp3 transcription factor
Biomedicines, Vol. 9, Núm. 2, pp. 1-20
2020
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Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion
Journal of Cell Biology, Vol. 219, Núm. 9
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Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens
Journal for immunotherapy of cancer, Vol. 8, Núm. 1
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Id1 and pd-1 combined blockade impairs tumor growth and survival of KRAS-mutant lung cancer by stimulating PD-l1 expression and tumor infiltrating CD8+ T cells
Cancers, Vol. 12, Núm. 11, pp. 1-22
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Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade
Nature cancer, Vol. 1, Núm. 1, pp. 75-85
2019
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FOXP3 Inhibitory Peptide P60 Increases Efficacy of Cytokine-induced Killer Cells against Renal and Pancreatic Cancer Cells
Anticancer Research, Vol. 39, Núm. 10, pp. 5369-5374